Cardiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, End of Keshavarz Boulevard, 1419733141, Tehran, Iran.
Radiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Int J Cardiovasc Imaging. 2021 May;37(5):1629-1636. doi: 10.1007/s10554-020-02148-1. Epub 2021 Jan 16.
To assess imaging data in COVID-19 patients and its association with clinical course and survival and 86 consecutive patients (52 males, 34 females, mean age = 58.8 year) with documented COVID-19 infection were included. Seventy-eight patients (91%) were in severe stage of the disease. All patients underwent transthoracic echocardiography. Mean LVEF was 48.1% and mean estimated systolic pulmonary artery pressure (sPAP) was 27.9 mmHg. LV diastolic dysfunction was mildly abnormal in 49 patients (57.6%) and moderately abnormal in 7 cases (8.2%). Pericardial effusion was present in 5/86 (minimal in size in 3 cases and mild- moderate in 2). In 32/86 cases (37.2%), the severity of infection progressed from "severe" to "critical". Eleven patients (12.8%) died. sPAP and computed tomography score were associated with disease progression (P value = 0.002, 0.002 respectively). Tricuspid annular plane systolic excursion (TAPSE) was significantly higher in patients with no disease progression compared with those who deteriorated (P value = 0.005). Pericardial effusion (minimal, mild or moderate) was detected more often in progressive disease (P = 0.03). sPAP was significantly lower among survivors (P value = 0.007). Echocardiographic findings (including systolic PAP, TAPSE and pericardial effusion), total CT score may have prognostic and therapeutic implication in COVID-19 patients.
评估 COVID-19 患者的影像学数据及其与临床病程和生存的关系,纳入了 86 例连续的 COVID-19 感染患者(52 名男性,34 名女性,平均年龄=58.8 岁)。78 例患者(91%)处于疾病的严重阶段。所有患者均接受了经胸超声心动图检查。平均 LVEF 为 48.1%,平均估计收缩期肺动脉压(sPAP)为 27.9mmHg。49 例(57.6%)患者左心室舒张功能轻度异常,7 例(8.2%)中度异常。心包积液 5/86 例(3 例为微量,2 例为少量-中度)。86 例中有 32 例(37.2%)病情从“严重”进展为“危急”。11 例(12.8%)患者死亡。sPAP 和计算机断层扫描评分与疾病进展相关(P 值分别为 0.002、0.002)。与病情恶化的患者相比,无病情进展的患者三尖瓣环平面收缩期位移(TAPSE)明显更高(P 值=0.005)。进展性疾病中更常检测到心包积液(微量、轻度或中度)(P=0.03)。幸存者的 sPAP 明显更低(P 值=0.007)。超声心动图表现(包括收缩期 PAP、TAPSE 和心包积液)、总 CT 评分可能对 COVID-19 患者具有预后和治疗意义。