Houlton P C, Downing J W, Buley R J, Brock-Utne J G
S Afr Med J. 1978 Nov 11;54(20):818-20.
Thiopentone (3,5 mg/kg) was compared with methohexitone (1 mg/kg) and 'low-dose' ketamine (1 mg/kg) for induction of obstetric anaesthesia. Anaesthesia was maintained with gas, oxygen, muscle relaxant and 0.6% enflurane. Fetal oxygenation was superior with thiopentone, but blood gas/acid base status was otherwise comparable among the different agents. Methohexitone and low-dose ketamine appear to offer reasonable alternatives to thiopentone for anaesthetic induction at caesarean section.
将硫喷妥钠(3.5毫克/千克)与甲己炔巴比妥(1毫克/千克)及“低剂量”氯胺酮(1毫克/千克)用于产科麻醉诱导进行比较。麻醉维持采用气体、氧气、肌肉松弛剂及0.6%安氟醚。硫喷妥钠组胎儿氧合情况更佳,但不同药物在血气/酸碱状态方面具有可比性。甲己炔巴比妥和低剂量氯胺酮似乎可作为剖宫产麻醉诱导时硫喷妥钠的合理替代药物。