Department of Oral Implantology, Stomatology Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Stomatology College, Zhejiang University, Hangzhou, China.
Clin Oral Implants Res. 2021 Apr;32(4):448-459. doi: 10.1111/clr.13714. Epub 2021 Feb 9.
To investigate the early bone formation in beagles with mini-lateral window sinus floor elevation and simultaneous implant placement.
Six beagles were selected for the split-mouth design procedures. In each animal, one maxillary recess received a 5 mm-diameter mini-round lateral osteotomy (test group), and the contralateral maxillary recess received a large rectangular osteotomy (10 mm long and 8 mm wide), (control group). Simultaneous implant installation was executed on bilateral maxillary recesses. Tetracycline and calcein dyes were administered on the 14th, 13th days and the 4th, 3rd days prior to sacrifice, respectively. After 8 weeks of healing, the beagles were euthanized for fluorescent labeling and histomorphometric analyses.
In both groups, new bone formation initiated from the circumferential native bone of the maxillary recesses and extended toward the central sub-recess cavities. The maxillary recesses with the mini-window procedures exhibited superior mineral apposition rate, bone formation rate, and the percentage of new bone area to those of the group exposed to large osteotomy procedure (p < .05). While there was no significant difference in the value of bone-to-implant contact, the mini-window group displayed a tendency for an increase in this aspect (p > .05). Bone formation rate and new bone amount were not statistically correlated with bone-to-implant contact (p > .05).
The hypothesis that mini-lateral window sinus floor elevation with simultaneous implant placement would improve early new bone formation in augmented sinus compared with large lateral window procedure is accepted.
研究小型侧开窗窦底提升并同期植入时比格犬的早期骨形成。
选择 6 只比格犬进行分侧设计实验。每只动物的一侧上颌窦接受 5mm 直径的迷你圆形侧切开术（实验组），对侧上颌窦接受大矩形切开术（10mm 长，8mm 宽）（对照组）。双侧上颌窦同时植入种植体。在处死前分别于第 14、13 天和第 4、3 天给予四环素和钙黄绿素染料。愈合 8 周后，处死比格犬进行荧光标记和组织形态计量学分析。
两组均从上颌窦的环形固有骨开始新骨形成，并向中央次级窦腔扩展。与接受大切开术的组相比，采用小窗口术式的上颌窦具有更高的矿化沉积率、骨形成率和新骨面积百分比（p<.05）。虽然骨-种植体接触率无显著差异，但小窗口组有增加的趋势（p>.05）。骨形成率和新骨量与骨-种植体接触率无统计学相关性（p>.05）。
接受小型侧开窗窦底提升并同期植入时会比大侧开窗术式更能改善增强窦内的早期新骨形成的假设被接受。
