Si Mi-Si, Mo Jia-Ji, Zhuang Long-Fei, Gu Ying-Xin, Qiao Shi-Chong, Lai Hong-Chang
Department of Oral and Maxilliofacial Implantology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Institute of Stomatology, Shanghai Jiaotong University, Shanghai, China.
Clin Oral Implants Res. 2015 Feb;26(2):197-203. doi: 10.1111/clr.12313. Epub 2013 Dec 20.
To evaluate implant stability and histological outcomes after osteotome sinus floor elevation (OSFE) procedure, and to compare new bone formation and implant osseointegration with and without grafting.
OSFE with simultaneous implant placement was conducted bilaterally on 6 Labrador dogs. Twenty-four implants were placed. The right side sinus (Group 1) was grafted with biphasic calcium phosphate (BCP), whereas the left side (Group 2) was left without any grafting materials. The animals were euthanized 8 and 24 weeks after surgery for histological and histomorphometric assessment. Bone-to-implant contact (BIC%), alveolar bone height (ABH), bone density (BD) and grafting material density (GMD) were measured. The implant stability (ISQ) was assessed using resonance frequency analysis (RFA) at implant placement and 1, 2, 4, 8, 12, 24 weeks after surgery.
Endo-sinus new bone with direct contact to implant surface were observed in two groups at both time points. ABH showed no difference between groups at both time points. BIC% and BD in Group 2 (40.05%, 35.90%) was higher than those in Group 1 (23.30%,25.59%) at 24 weeks. Significant shrinkage of grafting material was seen in Group 1. The GMD in Group 1 at 8 weeks was 24.35%, while it dropped to 19.90% at 24 weeks. The changing pattern of ISQ for both groups were similar.
Spontaneous new bone formation and better bone-to-implant contact were found for OSFE without grafting. The grafting material application during OSFE procedure showed no advantages in histological results.
评估骨凿上颌窦底提升术（OSFE）后种植体稳定性和组织学结果，并比较有无植骨情况下的新骨形成及种植体骨结合情况。
对6只拉布拉多犬双侧进行OSFE并同期植入种植体。共植入24枚种植体。右侧上颌窦（第1组）植入双相磷酸钙（BCP），而左侧（第2组）不植入任何植骨材料。术后8周和24周对动物实施安乐死，进行组织学和组织形态计量学评估。测量骨-种植体接触率（BIC%）、牙槽骨高度（ABH）、骨密度（BD）和植骨材料密度（GMD）。在种植体植入时以及术后1、2、4、8、12、24周，采用共振频率分析（RFA）评估种植体稳定性（ISQ）。
在两个时间点，两组均观察到与种植体表面直接接触的窦内新骨。两个时间点两组间ABH均无差异。术后24周时，第2组的BIC%（40.05%）和BD（35.90%）高于第1组（23.30%，25.59%）。第1组可见植骨材料明显收缩。第1组8周时的GMD为24.35%，而24周时降至19.90%。两组ISQ的变化模式相似。
未植骨的OSFE可实现自发新骨形成及更好的骨-种植体接触。OSFE过程中应用植骨材料在组织学结果方面无优势。
