Murata Mitsushige
Department of Laboratory Medicine, Tokai University Hachioji Hospital, Tokyo, Japan.
Keio J Med. 2021 Sep 25;70(3):60-67. doi: 10.2302/kjm.2020-0015-IR. Epub 2021 Jan 16.
Pulmonary hypertension (PH) is a progressive disease characterized by increased pulmonary vascular resistance that leads to right ventricular (RV) failure, a condition that determines its prognosis. This review focuses on the clinical value of the evaluation of RV function in PH. First, the pathophysiology of PH, including hemodynamics, RV function, and their interaction (known as ventriculoarterial coupling), are summarized. Next, non-invasive imaging modalities and the parameters of RV function, mainly assessed by echocardiography, are reviewed. Finally, the clinical impacts of RV function in PH are described. This review will compare the techniques that yield comprehensive information on RV function and their roles in the assessment of PH.
肺动脉高压(PH)是一种进行性疾病,其特征为肺血管阻力增加,进而导致右心室(RV)衰竭,这一状况决定了其预后。本综述聚焦于肺动脉高压中右心室功能评估的临床价值。首先,总结肺动脉高压的病理生理学,包括血流动力学、右心室功能及其相互作用(即心室动脉耦联)。其次,回顾主要通过超声心动图评估右心室功能的非侵入性成像方式及参数。最后,描述右心室功能在肺动脉高压中的临床影响。本综述将比较能提供有关右心室功能全面信息的技术及其在肺动脉高压评估中的作用。