Kouidere Abdelfatah, Khajji Bouchaib, Balatif Omar, Rachik Mostafa
Laboratory of Analysis Modeling and Simulation, Department of Mathematics and Computer Science, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca, Morocco.
Laboratory of Dynamical Systems, Mathematical Engineering Team (INMA), Department of Mathematics, Faculty of Sciences El Jadida, Chouaib Doukkali University, El Jadida, Morocco.
J Appl Math Comput. 2021;67(1-2):375-403. doi: 10.1007/s12190-020-01474-w. Epub 2021 Jan 11.
Diabetes is a disease which caused by socio-environmental and / or genetic factors. The negative effect of socio-environmental or lifestyle leads a susceptible individual to become a diabetic. On the one hand, social interaction wields a great deal of influence over lifestyle. On the other hand, genetic factors are the main cause of the birth diabetes genetic disorder. Considering these above mentioned factors. In the present paper, we study a discrete age continuous mathematical model that describes the dynamics of diabetics. We highlight the negative impact of socio-environmental on diabetic patients according to age groups. We also suggest an optimal strategy to implement the best campaigns of rising awareness that aims at protecting diabetic patients from the negative impact of a lifestyle that leads them to complications. In addition to psychological treatment and follow-up of diabetic patients with complications, an awareness campaign will also be carried out for people with potential diabetes that aims at educating them about the dangerous of diabetes and its complications. Pontryagin's maximum principle is used to characterize the optimal controls and the optimality system is solved by an iterative method. The numerical simulation is carried out using MATLAB.
糖尿病是一种由社会环境和/或遗传因素引起的疾病。社会环境或生活方式的负面影响会使易感个体患上糖尿病。一方面,社会交往对生活方式有很大影响。另一方面,遗传因素是先天性糖尿病遗传疾病的主要原因。考虑到上述因素,在本文中,我们研究了一个离散年龄连续数学模型,该模型描述了糖尿病患者的动态变化。我们根据年龄组突出了社会环境对糖尿病患者的负面影响。我们还提出了一种最优策略,以开展最佳的提高认识活动,旨在保护糖尿病患者免受导致并发症的生活方式的负面影响。除了对有并发症的糖尿病患者进行心理治疗和随访外,还将针对潜在糖尿病患者开展提高认识活动,旨在教育他们了解糖尿病及其并发症的危险性。庞特里亚金极大值原理用于刻画最优控制,最优性系统通过迭代方法求解。数值模拟使用MATLAB进行。