"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
General and Esophageal Surgery Clinic, "Sf Maria" Clinical Hospital, Bucharest, Romania.
J Med Life. 2020 Oct-Dec;13(4):442-448. doi: 10.25122/jml-2020-0160.
Reflux disease continues to be one of the most common pathologies in the world. There is much discussion regarding the mechanism of developing and the variety of possible symptoms. In recent years, the use of new technologies, like high-resolution manometry and pH impedance, brought new insights into this disease. Also, there are emerging therapies that are covering the gap between the patients treated with proton-pump inhibitor (PPI) therapy and those who benefit the most from laparoscopic treatment (hiatal hernia, complications of gastroesophageal reflux disease (GERD). Also, most of them are less invasive than a laparoscopic fundoplication. We present a short review of the treatment options in patients who need more than lifestyle changes and PPI therapy.
反流病仍然是世界上最常见的疾病之一。对于其发病机制和各种可能的症状，存在着大量的讨论。近年来，使用新的技术，如高分辨率测压法和 pH 阻抗法，为这种疾病带来了新的认识。此外，还出现了一些新兴的治疗方法，填补了质子泵抑制剂（PPI）治疗患者和最受益于腹腔镜治疗（食管裂孔疝、胃食管反流病（GERD）并发症）之间的空白。而且，它们中的大多数比腹腔镜胃底折叠术的创伤更小。我们对需要改变生活方式和 PPI 治疗以外的治疗选择的患者进行了简短的综述。
