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1
Reversal of neuromuscular block.神经肌肉阻滞的逆转。
BJA Educ. 2020 Aug;20(8):259-265. doi: 10.1016/j.bjae.2020.03.008. Epub 2020 Jul 1.
2
Reversal of rocuronium-induced neuromuscular block with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine.与新斯的明用于顺式阿曲库铵诱导的神经肌肉阻滞逆转相比，舒更葡糖用于罗库溴铵诱导的神经肌肉阻滞逆转更快。
Br J Anaesth. 2008 May;100(5):622-30. doi: 10.1093/bja/aen037. Epub 2008 Apr 2.
3
Reversal of Deep Pipecuronium-Induced Neuromuscular Block With Moderate Versus Standard Dose of Sugammadex: A Randomized, Double-Blind, Noninferiority Trial.罗库溴铵诱导的神经肌肉阻滞逆转：中剂量与标准剂量琥珀酸舒更葡糖钠的随机、双盲、非劣效性试验。
Anesth Analg. 2018 Dec;127(6):1344-1350. doi: 10.1213/ANE.0000000000003719.
4
Is lower-dose sugammadex a cost-saving strategy for reversal of deep neuromuscular block? Facts and fiction.较低剂量的舒更葡糖钠是逆转深度神经肌肉阻滞的一种节省成本策略吗？事实与假象。
BMC Anesthesiol. 2018 Nov 6;18(1):159. doi: 10.1186/s12871-018-0605-6.
5
A discrete event simulation model of clinical and operating room efficiency outcomes of sugammadex versus neostigmine for neuromuscular block reversal in Canada.加拿大使用舒更葡糖钠与新斯的明逆转神经肌肉阻滞的临床和手术室效率结果的离散事件模拟模型。
BMC Anesthesiol. 2016 Nov 16;16(1):114. doi: 10.1186/s12871-016-0281-3.
6
A Meta-Analysis on the Effect of Dexamethasone on the Sugammadex Reversal of Rocuronium-Induced Neuromuscular Block.地塞米松对舒更葡糖钠逆转罗库溴铵诱导的神经肌肉阻滞作用的荟萃分析
J Clin Med. 2020 Apr 24;9(4):1240. doi: 10.3390/jcm9041240.
7
A case series of re-establishment of neuromuscular block with rocuronium after sugammadex reversal.舒更葡糖钠逆转后使用罗库溴铵重新建立神经肌肉阻滞的病例系列
J Anesth. 2016 Jun;30(3):534-7. doi: 10.1007/s00540-016-2159-4. Epub 2016 Mar 7.
8
Efficacy of sugammadex for the reversal of moderate and deep rocuronium-induced neuromuscular block in patients pretreated with intravenous magnesium: a randomized controlled trial.舒更葡糖钠用于逆转静脉注射镁预处理患者中、深度罗库溴铵诱导的神经肌肉阻滞的疗效：一项随机对照试验。
Anesthesiology. 2014 Jul;121(1):59-67. doi: 10.1097/ALN.0000000000000204.
9
Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey.舒更葡糖钠，一种用于麻醉恒河猴中罗库溴铵诱导的神经肌肉阻滞的新型逆转剂。
Br J Anaesth. 2006 Apr;96(4):473-9. doi: 10.1093/bja/ael013. Epub 2006 Feb 7.
10
Dexamethasone does not diminish sugammadex reversal of neuromuscular block - clinical study in surgical patients undergoing general anesthesia.地塞米松不会减弱舒更葡糖钠对神经肌肉阻滞的逆转作用——对接受全身麻醉的外科患者的临床研究。
BMC Anesthesiol. 2016 Oct 21;16(1):101. doi: 10.1186/s12871-016-0254-6.

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1
Developing novel drugs to reverse neuromuscular block: do we need them?开发新型药物以逆转神经肌肉阻滞：我们需要它们吗？
Br J Anaesth. 2025 Jun;134(6):1591-1596. doi: 10.1016/j.bja.2025.03.006. Epub 2025 Apr 16.
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ClC-1 Inhibition as a Mechanism for Accelerating Skeletal Muscle Recovery After Neuromuscular Block in Rats.氯离子通道-1 抑制作为加速大鼠神经肌肉阻滞后骨骼肌恢复的机制。
Nat Commun. 2024 Oct 28;15(1):9289. doi: 10.1038/s41467-024-53237-x.
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Effect of sugammadex with neostigmine on postoperative bowel function and on recovery of neuromuscular functions: A randomized controlled trial.新斯的明联合琥珀酰明胶对术后肠功能和神经肌肉功能恢复的影响：一项随机对照试验。
Medicine (Baltimore). 2024 Sep 13;103(37):e39623. doi: 10.1097/MD.0000000000039623.
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The Influence of Acid-Base Balance on Anesthetic Muscle Relaxants: A Comprehensive Review on Clinical Applications and Mechanisms.酸碱平衡对麻醉肌肉松弛剂的影响：临床应用与机制的综合综述。
Med Sci Monit. 2024 Jul 1;30:e944510. doi: 10.12659/MSM.944510.
5
Neuromuscular block management: evidence-based principles and practice.神经肌肉阻滞管理：循证原则与实践
BJA Educ. 2024 Jan;24(1):13-22. doi: 10.1016/j.bjae.2023.10.005. Epub 2023 Nov 29.
6
Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review.残余肌松对围手术期医疗专业人员而言仍是安全隐患：一项全面综述。
J Clin Med. 2024 Feb 1;13(3):861. doi: 10.3390/jcm13030861.
7
General Anesthetic Care of Obese Patients Undergoing Surgery: A Review of Current Anesthetic Considerations and Recent Advances.肥胖患者手术的全身麻醉护理：当前麻醉考量及最新进展综述
Cureus. 2023 Jul 8;15(7):e41565. doi: 10.7759/cureus.41565. eCollection 2023 Jul.
8
Association between one-session bilateral whole-lung lavage and periprocedural complications in patients with pulmonary alveolar proteinosis: a retrospective cohort study.一次双侧全肺灌洗术与肺泡蛋白沉积症患者围手术期并发症的关系：一项回顾性队列研究。
Orphanet J Rare Dis. 2023 Apr 20;18(1):91. doi: 10.1186/s13023-023-02691-9.

本文引用的文献

1
Neostigmine versus sugammadex: the tide may be turning, but we still need to navigate the winds.新斯的明与舒更葡糖钠：形势或许正在转变，但我们仍需应对各种情况。
Br J Anaesth. 2020 May;124(5):504-507. doi: 10.1016/j.bja.2020.02.021. Epub 2020 Mar 27.
2
Comparison of incidence of anaphylaxis between sugammadex and neostigmine: a retrospective multicentre observational study.舒更葡糖与新斯的明致过敏反应发生率的比较：一项回顾性多中心观察性研究。
Br J Anaesth. 2020 Feb;124(2):154-163. doi: 10.1016/j.bja.2019.10.016. Epub 2019 Nov 30.
3
Use of a train-of-four ratio of 0.95 versus 0.9 for tracheal extubation: an exploratory analysis of POPULAR data.使用肌松监测仪监测下的四成串刺激（TOF）比值 0.95 与 0.9 用于气管拔管的比较：POPULAR 数据的探索性分析。
Br J Anaesth. 2020 Jan;124(1):63-72. doi: 10.1016/j.bja.2019.08.023. Epub 2019 Oct 10.
4
Sugammadex hypersensitivity and underlying mechanisms: a randomised study of healthy non-anaesthetised volunteers.苏伽达ex 过敏反应及其潜在机制：一项健康非麻醉志愿者的随机研究。
Br J Anaesth. 2018 Oct;121(4):758-767. doi: 10.1016/j.bja.2018.05.057. Epub 2018 Jul 13.
5
Hypersensitivity incidence after sugammadex administration in healthy subjects: a randomised controlled trial.健康受试者中使用 sugammadex 后过敏反应的发生率：一项随机对照试验。
Br J Anaesth. 2018 Oct;121(4):749-757. doi: 10.1016/j.bja.2018.05.056. Epub 2018 Aug 23.
6
Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study.肌松药使用后全身麻醉后肺部并发症（POPULAR）：一项多中心、前瞻性观察研究。
Lancet Respir Med. 2019 Feb;7(2):129-140. doi: 10.1016/S2213-2600(18)30294-7. Epub 2018 Sep 14.
7
Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine.灵长类动物恒河猴中 CW 1759-50 的临床前药理学研究，一种新型超短效非去极化神经肌肉阻断剂，可被 L-半胱氨酸降解和拮抗。
Anesthesiology. 2018 Nov;129(5):970-988. doi: 10.1097/ALN.0000000000002408.
8
Sugammadex-induced bradycardia and asystole: how great is the risk?舒更葡糖钠引起的心动过缓和心搏停止：风险有多大？
Br J Anaesth. 2018 Jul;121(1):8-12. doi: 10.1016/j.bja.2018.03.003. Epub 2018 Apr 13.
9
Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6).麻醉、手术和危及生命的过敏反应：第 6 次国家审计项目（NAP6）中围手术期过敏反应的流行病学和临床特征。
Br J Anaesth. 2018 Jul;121(1):159-171. doi: 10.1016/j.bja.2018.04.014. Epub 2018 May 21.
10
Reversal of residual neuromuscular block: complications associated with perioperative management of muscle relaxation.残余神经肌肉阻滞的逆转：与肌肉松弛围手术期管理相关的并发症。
Br J Anaesth. 2017 Dec 1;119(suppl_1):i53-i62. doi: 10.1093/bja/aex318.

Reversal of neuromuscular block.

作者信息

Hunter J M

机构信息

University of Liverpool, Liverpool, UK.

出版信息

BJA Educ. 2020 Aug;20(8):259-265. doi: 10.1016/j.bjae.2020.03.008. Epub 2020 Jul 1.

DOI:10.1016/j.bjae.2020.03.008
PMID:33456959
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7807829/
Abstract
摘要