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使用外部治疗计划系统准确估算每日放疗剂量。

Accurate estimation of daily delivered radiotherapy dose with an external treatment planning system.

作者信息

Kanehira Takahiro, Svensson Stina, van Kranen Simon, Sonke Jan-Jakob

机构信息

Department of Radiation Oncology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

RaySearch Laboratories AB, Stockholm, Sweden.

出版信息

Phys Imaging Radiat Oncol. 2020 May 29;14:39-42. doi: 10.1016/j.phro.2020.05.005. eCollection 2020 Apr.

DOI:10.1016/j.phro.2020.05.005
PMID:33458312
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7807587/
Abstract

Accurate estimation of the daily radiotherapy dose is challenging in a multi-institutional collaboration when the institution specific treatment planning system (TPS) is not available. We developed and evaluated a method to tackle this problem. Residual errors in daily estimations were minimized with single correction based on the planned dose. For nine patients, medians of the absolute estimation errors for targets and OARs were less than 0.2 Gy ( ), 0.3 Gy ( ), and 0.1 Gy ( ). In general, mimicking errors were significantly smaller than dose differences caused by anatomical changes. The demonstrated accuracy may facilitate dose accumulation in a multi-institutional/multi-vendor setting.

摘要

在多机构合作中,如果无法获取各机构特定的治疗计划系统(TPS),准确估算每日放疗剂量具有挑战性。我们开发并评估了一种解决此问题的方法。基于计划剂量进行单次校正,可将每日估算中的残余误差降至最低。对于9名患者,靶区和危及器官绝对估算误差的中位数分别小于0.2 Gy( )、0.3 Gy( )和0.1 Gy( )。一般来说,模拟误差显著小于由解剖结构变化引起的剂量差异。所展示的准确性可能有助于在多机构/多供应商环境中进行剂量累积。

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本文引用的文献

1
Differences between planned and delivered dose for head and neck cancer, and their consequences for normal tissue complication probability and treatment adaptation.头颈部癌症计划剂量与实际剂量的差异,及其对正常组织并发症概率和治疗适应的影响。
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Delivered dose can be a better predictor of rectal toxicity than planned dose in prostate radiotherapy.
在前列腺放疗中,实际给予剂量比计划剂量更能准确预测直肠毒性。
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Helical tomotherapy to LINAC plan conversion utilizing RayStation Fallback planning.利用RayStation备用计划将螺旋断层放射治疗转换为直线加速器计划。
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Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes.采用自适应放射治疗减少头颈部边缘:治疗计划针对解剖结构变化的稳健性
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Evaluation of dual-arc VMAT radiotherapy treatment plans automatically generated via dose mimicking.通过剂量模拟自动生成的双弧容积调强弧形放疗治疗计划的评估
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Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?识别可能受益于自适应放疗的患者:头颈部放疗中危及器官的解剖和剂量学改变的文献是否提供了有助于指导的信息?
Radiother Oncol. 2015 Jun;115(3):285-94. doi: 10.1016/j.radonc.2015.05.018. Epub 2015 Jun 17.
9
Toward adaptive radiotherapy for head and neck patients: Uncertainties in dose warping due to the choice of deformable registration algorithm.迈向头颈部患者的自适应放射治疗:由于可变形配准算法的选择导致剂量扭曲的不确定性。
Med Phys. 2015 Feb;42(2):760-9. doi: 10.1118/1.4905050.
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Deformable image registration for adaptive radiation therapy of head and neck cancer: accuracy and precision in the presence of tumor changes.用于头颈癌自适应放射治疗的可变形图像配准:肿瘤变化情况下的准确性和精确性。
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