Wyatt Jonathan, Hedley Stephen, Johnstone Emily, Speight Richard, Kelly Charles, Henry Ann, Short Susan, Murray Louise, Sebag-Montefiore David, McCallum Hazel
Northern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.
Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
Phys Imaging Radiat Oncol. 2018 May 1;6:31-38. doi: 10.1016/j.phro.2018.04.005. eCollection 2018 Apr.
Magnetic Resonance (MR)-only radiotherapy requires geometrically accurate MR images over the full scanner Field of View (FoV). This study aimed to investigate the repeatability of distortion measurements made using a commercial large FoV phantom and analysis software and the sensitivity of these measurements to small set-up errors.
Geometric distortion was measured using a commercial phantom and software with 2D and 3D acquisition sequences on three different MR scanners. Two sets of repeatability measurements were made: three scans acquired without moving the phantom between scans (single set-up) and five scans acquired with the phantom re-set up in between each scan (repeated set-up). The set-up sensitivity was assessed by scanning the phantom with an intentional 1 mm lateral offset and independently an intentional 1° rotation.
The mean standard deviation of distortion for all phantom markers for the repeated set-up scans was for all scanners and sequences. For the lateral offset scan of the markers agreed within two standard deviations of the mean of the repeated set-up scan (median of all scanners and sequences, range 78%-93%). For the 1° rotation scan, 80% of markers agreed within two standard deviations of the mean (range 69%-93%).
Geometric distortion measurements using a commercial phantom and associated software appear repeatable, although with some sensitivity to set-up errors. This suggests the phantom and software are appropriate for commissioning a MR-only radiotherapy workflow.
仅基于磁共振(MR)的放射治疗需要在整个扫描仪视野(FoV)内获得几何精度准确的MR图像。本研究旨在调查使用商用大视野体模和分析软件进行的畸变测量的可重复性,以及这些测量对小的摆位误差的敏感性。
使用商用体模和软件,在三台不同的MR扫描仪上通过二维和三维采集序列测量几何畸变。进行了两组可重复性测量:在扫描之间不移动体模进行三次扫描(单次摆位),以及在每次扫描之间重新摆位体模进行五次扫描(重复摆位)。通过有意将体模横向偏移1毫米和独立有意旋转1°来扫描体模,评估摆位敏感性。
对于所有扫描仪和序列,重复摆位扫描中所有体模标记的畸变平均标准差为 。对于横向偏移1毫米的扫描, 的标记在重复摆位扫描平均值的两个标准差内一致(所有扫描仪和序列的中位数,范围78%-93%)。对于1°旋转扫描,80%的标记在平均值的两个标准差内一致(范围69%-93%)。
使用商用体模和相关软件进行的几何畸变测量似乎具有可重复性,尽管对摆位误差有一定敏感性。这表明该体模和软件适用于调试仅基于MR的放射治疗工作流程。