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金属存在情况下的结构描绘——一项使用单能和双能计算机断层扫描并有无金属伪影减少技术的对比体模研究

Structure delineation in the presence of metal - A comparative phantom study using single and dual-energy computed tomography with and without metal artefact reduction.

作者信息

Pettersson Erik, Bäck Anna, Björk-Eriksson Thomas, Lindencrona Ulrika, Petruson Karin, Thilander-Klang Anne

机构信息

Department of Diagnostic Radiation Physics, Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, SE-41345 Gothenburg, Sweden.

Department of Therapeutic Radiation Physics, Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, SE-41345 Gothenburg, Sweden.

出版信息

Phys Imaging Radiat Oncol. 2019 Feb 13;9:43-49. doi: 10.1016/j.phro.2019.01.001. eCollection 2019 Jan.

Abstract

BACKGROUND AND PURPOSE

Metal artefacts in computed tomography (CT) images impairs structure delineation. These artefacts can potentially be reduced with dual-energy CT (DECT) with or without using metal artefact reduction (MAR). The purpose was to investigate how structure delineation in DECT with or without MAR and single-energy CT (SECT) images were affected by metals.

MATERIALS AND METHODS

A phantom with known irregular structures was developed. Reference structures were determined from a low-noise scan without metal. Bilateral hip prostheses were simulated with steel or titanium inserts. The phantom was scanned with SECT and fast-kV switching DECT with optional MAR. Four radiation oncologists delineated the structures in two phantom set-ups. Delineated structures were evaluated with Dice similarity coefficient (DSC) and Hausdorff distance relative to the reference structures.

RESULTS

With titanium inserts, more structures were detected for non-MAR DECT compared to SECT while the same or less were detected with steel inserts. MAR improved delineation in DECT images. For steel inserts, three structures in the region of artefacts, were delineated by at least two oncologists with MAR-DECT compared to none with non-MAR DECT or SECT. The highest values of DSC for MAR-DECT were 0.69, 0.81 and 0.77 for those structures.

CONCLUSIONS

Delineation was improved with non-MAR DECT compared to SECT, especially for titanium inserts. A larger improvement was seen with the use of MAR for both steel and titanium inserts. The improvement was dependent on the location of the structure relative to the inserts, and the structure contrast relative to the background.

摘要

背景与目的

计算机断层扫描(CT)图像中的金属伪影会影响结构的勾画。使用或不使用金属伪影减少(MAR)技术的双能量CT(DECT)有可能减少这些伪影。本研究旨在探讨使用或不使用MAR的DECT以及单能量CT(SECT)图像中的结构勾画如何受到金属的影响。

材料与方法

制作了一个具有已知不规则结构的体模。通过无金属的低噪声扫描确定参考结构。用钢或钛植入物模拟双侧髋关节假体。使用SECT和具有可选MAR功能的快速kV切换DECT对体模进行扫描。四名放射肿瘤学家在两种体模设置中勾画结构。使用Dice相似系数(DSC)和相对于参考结构的豪斯多夫距离对勾画的结构进行评估。

结果

对于钛植入物,与SECT相比,未使用MAR的DECT检测到更多结构,而对于钢植入物,检测到的结构相同或更少。MAR改善了DECT图像中的勾画。对于钢植入物,在伪影区域的三个结构,至少有两名肿瘤学家使用MAR-DECT进行了勾画,而未使用MAR的DECT或SECT均未检测到。这些结构的MAR-DECT的最高DSC值分别为0.69、0.81和0.77。

结论

与SECT相比,未使用MAR的DECT改善了勾画效果,尤其是对于钛植入物。对于钢和钛植入物,使用MAR都有更大的改善。这种改善取决于结构相对于植入物的位置以及相对于背景的结构对比度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/7807554/122952dbfe2c/gr1.jpg

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