Olsson Lars E, Johansson Mikael, Zackrisson Björn, Blomqvist Lennart K
Department of Medical Radiation Physics, Translational Medicine, Lund University, Sweden.
Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden.
Phys Imaging Radiat Oncol. 2019 Feb 25;9:50-57. doi: 10.1016/j.phro.2019.02.001. eCollection 2019 Jan.
Recently, the interest to integrate magnetic resonance imaging (MRI) in radiotherapy for prostate cancer has increased considerably. MRI can contribute in all steps of the radiotherapy workflow from diagnosis, staging, and target definition to treatment follow-up. Of particular interest is the ability of MRI to provide a wide range of functional measures. The complexity of MRI as an imaging modality combined with the growing interest of the application to prostate cancer radiotherapy, emphasize the need for dedicated education within the radiation oncology community. In this context, an overview of the most common as well as a few upcoming functional MR imaging techniques is presented: the basic methodology and measurement is described, the link between the functional measures and the underlying biology is established, and finally relevant applications of functional MRI useful for prostate cancer radiotherapy are given.
最近，将磁共振成像（MRI）整合到前列腺癌放射治疗中的兴趣显著增加。MRI在放射治疗工作流程的各个步骤中都能发挥作用，从诊断、分期、靶区定义到治疗随访。MRI能够提供广泛的功能测量这一特性尤其令人关注。MRI作为一种成像方式的复杂性，再加上其在前列腺癌放射治疗应用方面日益增长的兴趣，凸显了放射肿瘤学界进行专门教育的必要性。在此背景下，本文将概述最常见以及一些即将出现的功能磁共振成像技术：描述其基本方法和测量方法，建立功能测量与潜在生物学之间的联系，并最终给出功能MRI在前列腺癌放射治疗中的相关应用。
