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脑静脉血栓形成的临床和流行病学特征。沙特阿拉伯阿西尔地区的一项多中心回顾性研究。

Clinical and epidemiological profile of cerebral venous thrombosis. A Multicenter retrospective study in Aseer Region Saudi Arabi.

机构信息

Neurology Resident, Armed Forces Hospital-Southern Region, King Fahad Hospital, Jeddah, Kingdom of Saudi Arabia.

出版信息

Neurosciences (Riyadh). 2020 Oct;25(5):380-385. doi: 10.17712/nsj.2020.5.20200028.

Abstract

OBJECTIVE

To assess the epidemiological pattern and correlates with the clinical outcome of Cerebral venous thrombosis (CVT) in Abha, Kingdom of Saudi Arabia.

METHODS

A retrospective record_based cohort design was conducted including all patients admitted with diagnosis of CVT in 2 main tertiary hospitals in Aseer Region between 2015 to the end of 2018. The study hospitals were Aseer Central Hospital and Armed Forces Hospitals Southern Region. The data were collected by structured data sheets, including sociodemographic data. Assessment of known risk factors for CVT, clinical presentation, treatment received, and clinical outcome after treatment were extracted.

RESULTS

The study included 119 patients with CVT, whose ages ranged from 15 to 97 years, with a mean age of 35.5-/+14.1 years. Majority of the patients were females (81.5%). Headache was the most presenting (82.4%) symptom, followed by vomiting (30.3%) and a decreased level of consciousness. Thirty_three cases (27.7%) had complications, and recanalization was recorded among 92 cases (94.8%) based on follow up vascular imaging.

CONCLUSION

The study revealed that most of the cases of CVT had favorable clinical outcome and recanalization, especially those who had a shorter duration untildiagnosis. Young females were the most affected group.

摘要

目的

评估沙特阿拉伯阿巴哈地区脑静脉血栓形成(CVT)的流行病学模式及其与临床结局的相关性。

方法

采用回顾性基于记录的队列设计,纳入 2015 年至 2018 年底在阿西尔地区 2 家主要三级医院住院诊断为 CVT 的所有患者。研究医院为阿西尔中央医院和武装部队南部地区医院。通过结构化数据表收集数据,包括社会人口统计学数据。提取已知 CVT 危险因素、临床表现、治疗方法和治疗后临床结局的评估。

结果

本研究共纳入 119 例 CVT 患者,年龄 15 至 97 岁,平均年龄 35.5-/+14.1 岁。大多数患者为女性(81.5%)。头痛是最常见的(82.4%)症状,其次是呕吐(30.3%)和意识水平降低。33 例(27.7%)出现并发症,92 例(94.8%)根据随访血管成像显示再通。

结论

该研究表明,大多数 CVT 患者的临床结局和再通良好,尤其是那些诊断时间较短的患者。年轻女性是最易受影响的群体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4176/8015591/ffaf93e80ab5/Neurosciences-25-380-g001.jpg

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