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SARS-CoV-2 疫苗:成就斐然,仍有许多需要学习。

SARS-CoV-2 Vaccines: Much Accomplished, Much to Learn.

机构信息

the Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland (M.C., H.C.L., A.S.F.).

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland (B.S.G.).

出版信息

Ann Intern Med. 2021 May;174(5):687-690. doi: 10.7326/M21-0111. Epub 2021 Jan 19.

Abstract

As COVID vaccines roll out, internists and other health care providers are being turned to as trusted sources of information for patients and communities. Here, experts from NIAID outline the current state of knowledge regarding such vaccines. They contrast vaccine platforms, summarize clinical trial data regarding efficacy and safety, and comment on key questions including the ability of current vaccines to protect against infection and to decrease the prevalence of virus in the community.

摘要

随着 COVID 疫苗的推出,内科医生和其他医疗保健提供者正成为患者和社区信任的信息来源。在这里,NIAID 的专家概述了当前关于此类疫苗的知识状况。他们对比了疫苗平台,总结了关于疗效和安全性的临床试验数据,并就当前疫苗预防感染和减少社区病毒流行的能力等关键问题发表了评论。

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