Fava G, Galli L, Pollini C, Liverta C, Vicari A, Pontiroli A E
J Int Med Res. 1977;5(5):301-7. doi: 10.1177/030006057700500503.
In a double-blind trial carried out on 60 patients with osteoarthritis at various localizations, ketoprofen (Orudis), administered as a single nightly 100 mg suppository for ten days, was significantly more active and better tolerated than indomethacin, administered in the same way. Patient's and doctor's assessment was also in favour of Orudis. Laboratory examinations were not affected by either drug.
在一项针对60名不同部位骨关节炎患者的双盲试验中,每晚单次给予100毫克酮洛芬栓剂(奥鲁地),持续十天,其疗效显著优于以同样方式给药的吲哚美辛,且耐受性更好。患者和医生的评估也都倾向于奥鲁地。两种药物对实验室检查均无影响。