Nguyen Tuyet T A, Nguyen Hai L, Pham Tuyen N K, Nguyen Phung K P, Huynh Tuyet T N, Sichaem Jirapast, Do Lien T M
Department of Chemistry, Ho Chi Minh City University of Education, 748355, Viet Nam.
Sai Gon University, Ho Chi Minh City 748355, Viet Nam.
Fitoterapia. 2021 Mar;149:104832. doi: 10.1016/j.fitote.2021.104832. Epub 2021 Jan 16.
In an effort to identify natural bioactive compounds, three new flavonoids (1-3) and six known compounds (4-9) were isolated from the stem bark of Bougainvillea spectabilis. The structures of these compounds were accomplished using comprehensive spectroscopic methods, including 1D and 2D NMR spectra with references to the literatures, as well as high-resolution mass spectrometric analysis. Their cytotoxicity against KB and HeLa S-3 cell lines was also evaluated.
为了鉴定天然生物活性化合物,从叶子花属植物叶子花的茎皮中分离出了三种新的黄酮类化合物(1-3)和六种已知化合物(4-9)。这些化合物的结构通过综合光谱方法确定,包括参考文献的一维和二维核磁共振光谱以及高分辨率质谱分析。还评估了它们对KB和HeLa S-3细胞系的细胞毒性。