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澳大利亚北部地区的 ABO 和 Rh(D)血型。

ABO and Rhesus D blood groups in the Northern Territory of Australia.

机构信息

Division of Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Menzies School of Health Research, Darwin, Northern Territory, Australia.

出版信息

Intern Med J. 2021 Sep;51(9):1485-1489. doi: 10.1111/imj.15199.

Abstract

BACKGROUND

There are no contemporary published data on the frequency of the ABO and Rhesus D (RhD) blood groups in the Northern Territory (NT) of Australia, particularly for the large Aboriginal population.

AIMS

To establish the frequencies of ABO and RhD blood groups in the NT Aboriginal and non-Aboriginal populations in order to aid transfusion inventory management and clinical practice.

METHODS

Retrospective data were collected from 1 January 2012 to 31 December 2012. All patients with a blood group sample processed by the NT public hospital laboratories and a recorded ABO and RhD report were included. Results were analysed using Stata 14.

RESULTS

The Aboriginal and non-Aboriginal populations had significantly different ABO and RhD distributions (P < 0.001). For Aboriginal individuals, 955/1686 (56.6%) were group O and 669/1686 (39.7%) were group A. In non-Aboriginal individuals, 1201/2657 (45.2%) were group O and 986/2657 (37.1%) were group A. We found that 1646/1686 (97.6%) of Aboriginal individuals were RhD positive, compared with 2225/2657 (83.7%) of non-Aboriginal individuals. Only 62/1686 (3.7%) of Aboriginal individuals were group B or AB, compared with 470/2657 (17.7%) of non-Aboriginal individuals. In Aboriginal individuals we found that group O was more common than A in the 'Northern' NT, whereas there was similar distribution of the groups in 'Central Australia'.

CONCLUSIONS

We found a significant difference in ABO and RhD blood groups between Aboriginal and non-Aboriginal individuals in the NT (P < 0.001). These findings will aid transfusion inventory management, allowing us to plan supply of blood products and reduce waste.

摘要

背景

目前尚无关于澳大利亚北领地(NT)ABO 和 RhD(RhD)血型频率的当代文献,尤其是针对庞大的原住民人口。

目的

确定 NT 原住民和非原住民人群的 ABO 和 RhD 血型频率,以帮助输血库存管理和临床实践。

方法

回顾性收集 2012 年 1 月 1 日至 2012 年 12 月 31 日的数据。所有在 NT 公立医院实验室进行血型样本处理且有 ABO 和 RhD 报告记录的患者均纳入研究。使用 Stata 14 进行数据分析。

结果

原住民和非原住民人群的 ABO 和 RhD 分布存在显著差异(P < 0.001)。在原住民个体中,955/1686(56.6%)为 O 型,669/1686(39.7%)为 A 型。在非原住民个体中,1201/2657(45.2%)为 O 型,986/2657(37.1%)为 A 型。我们发现 1646/1686(97.6%)的原住民个体 RhD 阳性,而 2225/2657(83.7%)的非原住民个体 RhD 阳性。在原住民个体中,仅 62/1686(3.7%)为 B 型或 AB 型,而非原住民个体中为 470/2657(17.7%)。在原住民个体中,我们发现“北部”NT 中 O 型比 A 型更常见,而“中部澳大利亚”的血型分布则相似。

结论

我们发现 NT 原住民和非原住民人群的 ABO 和 RhD 血型存在显著差异(P < 0.001)。这些发现将有助于输血库存管理,使我们能够计划血液制品的供应,减少浪费。

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