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COVID-19 相关儿童多系统炎症综合征在新生儿中表现为持续性肺动脉高压。

COVID-19-Related Potential Multisystem Inflammatory Syndrome in Childhood in a Neonate Presenting as Persistent Pulmonary Hypertension of the Newborn.

机构信息

From the Department of Pediatrics, Apollo Hospitals (Unit: International Hospital), Guwahati, Assam, India.

Department of Paediatrics, Yeovil District Hospital, Yeovil, United Kingdom.

出版信息

Pediatr Infect Dis J. 2021 Apr 1;40(4):e162-e164. doi: 10.1097/INF.0000000000003054.

Abstract

A term infant with persistent pulmonary hypertension of newborn developed clinical and laboratory features of multisystem inflammatory syndrome in childhood (MIS-C) between days 12 and 14. Mother and baby were anti-SARS-Coronavirus-2 (SARS-CoV-2) IgG positive and anti-SARS-CoV-2 IgM negative on day 18, with negative COVID-19 PCR on repeated testing; possible first documentation of neonatal MIS-C following passive transfer of maternal antibodies.

摘要

一名患有持续性新生儿肺动脉高压的足月婴儿,在第 12 天至第 14 天期间出现了儿童多系统炎症综合征(MIS-C)的临床和实验室特征。母亲和婴儿在第 18 天 IgG 呈抗严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)阳性,IgM 呈抗 SARS-CoV-2 阴性,重复检测 COVID-19 PCR 均为阴性;这可能是首例通过母体抗体被动转移而导致新生儿 MIS-C 的病例。

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