Institute for Clinical Research, National Institutes of Health, Ministry of Health, Selangor, Malaysia.
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
PLoS One. 2021 Jan 19;16(1):e0245448. doi: 10.1371/journal.pone.0245448. eCollection 2021.
Risk of readmissions is an important quality indicator for stroke care. Such information is limited among low- and middle-income countries. We assessed the trends for 28-day readmissions after a stroke in Malaysia from 2008 to 2015 and evaluated the causes and factors associated with readmissions in 2015.
Using the national hospital admission records database, we included all stroke patients who were discharged alive between 2008 and 2015 for this secondary data analysis. The risk of readmissions was described in proportion and trends. Reasons were coded according to the International Classification of Diseases, 10th Edition. Multivariable logistic regression was performed to identify factors associated with readmissions.
Among 151729 patients, 11 to 13% were readmitted within 28 days post-discharge from their stroke events each year. The trend was constant for ischemic stroke but decreasing for hemorrhagic stroke. The leading causes for readmissions were recurrent stroke (32.1%), pneumonia (13.0%) and sepsis (4.8%). The risk of 28-day readmission was higher among those with stroke of hemorrhagic (adjusted odds ratio (AOR): 1.52) and subarachnoid hemorrhage (AOR: 2.56) subtypes, and length of index admission >3 days (AOR: 1.48), but lower among younger age groups of 35-64 (AORs: 0.61-0.75), p values <0.001.
The risk of 28-day readmission remained constant from 2008 to 2015, where one in eight stroke patients required readmission, mainly attributable to preventable causes. Age, ethnicity, stroke subtypes and duration of the index admission influenced the risk of readmission. Efforts should focus on minimizing potentially preventable admissions, especially among those at higher risk.
再入院风险是评估卒中医疗质量的重要指标,但在中低收入国家,相关信息较为有限。本研究旨在评估 2008 至 2015 年马来西亚卒中患者 28 天内再入院的变化趋势,并分析 2015 年再入院的原因和相关因素。
本研究采用国家住院记录数据库,对 2008 至 2015 年期间所有存活出院的卒中患者进行二次数据分析。使用比例和趋势描述再入院风险。再入院原因根据国际疾病分类第 10 版进行编码。采用多变量逻辑回归分析确定与再入院相关的因素。
在 151729 例患者中,每年有 11%至 13%的患者在卒中发病后 28 天内再次入院。缺血性卒中的再入院趋势保持稳定,而出血性卒中的再入院趋势则呈下降趋势。导致再入院的主要原因是卒中复发(32.1%)、肺炎(13.0%)和败血症(4.8%)。与出血性(调整优势比(aOR):1.52)和蛛网膜下腔出血(aOR:2.56)亚型以及住院时间>3 天(aOR:1.48)的卒中患者相比,28 天内再入院的风险更高,而年龄在 35-64 岁之间的患者(aORs:0.61-0.75)则较低,p 值均<0.001。
2008 至 2015 年期间,28 天内再入院的风险保持稳定,每 8 例卒中患者中就有 1 例需要再次入院,主要归因于可预防的原因。年龄、种族、卒中亚型和住院时间长短均影响再入院风险。应重点减少潜在可预防的再入院,尤其是高危人群。