Berry Jay G, Gay James C, Joynt Maddox Karen, Coleman Eric A, Bucholz Emily M, O'Neill Margaret R, Blaine Kevin, Hall Matthew
Division of General Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.
Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
BMJ. 2018 Feb 27;360:k497. doi: 10.1136/bmj.k497.
To assess trends in and risk factors for readmission to hospital across the age continuum.
Retrospective analysis.
31 729 762 index hospital admissions for all conditions in 2013 from the US Agency for Healthcare Research and Quality Nationwide Readmissions Database.
30 day, all cause, unplanned hospital readmissions. Odds of readmission were compared by patients' age in one year epochs with logistic regression, accounting for sex, payer, length of stay, discharge disposition, number of chronic conditions, reason for and severity of admission, and data clustering by hospital. The middle (45 years) of the age range (0-90+ years) was selected as the age reference group.
The 30 day unplanned readmission rate following all US index admissions was 11.6% (n=3 678 018). Referenced by patients aged 45 years, the adjusted odds ratio for readmission increased between ages 16 and 20 years (from 0.70 (95% confidence interval 0.68 to 0.71) to 1.04 (1.02 to 1.06)), remained elevated between ages 21 and 44 years (range 1.02 (1.00 to 1.03) to 1.12 (1.10 to 1.14)), steadily decreased between ages 46 and 64 years (range 1.02 (1.00 to 1.04) to 0.91 (0.90 to 0.93)), and decreased abruptly at age 65 years (0.78 (0.77 to 0.79)), after which the odds remained relatively constant with advancing age. Across all ages, multiple chronic conditions were associated with the highest adjusted odds of readmission (for example, 3.67 (3.64 to 3.69) for six or more versus no chronic conditions). Among children, young adults, and middle aged adults, mental health was one of the most common reasons for index admissions that had high adjusted readmission rates (≥75th centile).
The likelihood of readmission was elevated for children transitioning to adulthood, children and younger adults with mental health disorders, and patients of all ages with multiple chronic conditions. Further attention to the measurement and causes of readmission and opportunities for its reduction in these groups is warranted.
评估各年龄段患者再次入院的趋势及风险因素。
回顾性分析。
来自美国医疗保健研究与质量局全国再入院数据库的2013年31729762例各类疾病的首次住院病例。
30天内全因非计划再次入院情况。采用逻辑回归分析按患者年龄逐年比较再入院几率,并对性别、付款人、住院时间、出院处置方式、慢性病数量、入院原因及严重程度以及医院数据聚类进行校正。选择年龄范围(0 - 90岁以上)中间值(45岁)作为年龄参照组。
美国所有首次住院病例后的30天非计划再入院率为11.6%(n = 3678018)。以45岁患者为参照,16至20岁之间再入院校正比值比升高(从0.70(95%置信区间0.68至0.71)升至1.04(1.02至1.06)),21至44岁之间仍保持升高(范围1.02(1.00至1.03)至1.12(1.10至1.14)),46至64岁之间稳步下降(范围1.02(1.00至1.04)至0.91(0.90至0.93)),65岁时急剧下降(0.78(0.77至0.79)),此后随着年龄增长几率保持相对稳定。在所有年龄段中,多种慢性病与最高的再入院校正几率相关(例如,有六种或更多慢性病与无慢性病相比为3.67(3.64至3.69))。在儿童、年轻成年人和中年成年人中,心理健康是首次住院且再入院校正率较高(≥第75百分位数)的最常见原因之一。
向成年过渡的儿童、患有精神疾病的儿童和年轻成年人以及患有多种慢性病的各年龄段患者再入院可能性升高。有必要进一步关注这些人群再入院的测量方法、原因及降低再入院率的机会。