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2020 年 3 月至 6 月期间,英国一家大型监狱内发生了 COVID-19 疫情,该监狱内有大量弱势成年人,对此次疫情爆发的调查和筛查活动。

COVID-19 within a large UK prison with a high number of vulnerable adults, march to june 2020: An outbreak investigation and screening event.

机构信息

East of England Field Service, Public Health England, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge, CB2 0SR, United Kingdom; East of England Health Protection Team, Public Health England, Second Floor, Goodman House, Station Approach, Harlow, Essex, CM20 2ET, United Kingdom.

East of England Field Service, Public Health England, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge, CB2 0SR, United Kingdom.

出版信息

Int J Infect Dis. 2021 Mar;104:349-353. doi: 10.1016/j.ijid.2021.01.027. Epub 2021 Jan 16.

Abstract

OBJECTIVE

To describe the public health response to COVID-19 within a large prison with a high number of clinically vulnerable residents.

DESIGN

An outbreak investigation was undertaken among all residents and staff. A screening event involved nose and throat swab samples from residents and staff, examined by polymerase chain reaction (PCR). An electronic questionnaire regarding risk factors was distributed to staff.

RESULTS

58 residents out of 1,156 (5.0%, 95% CI: 3.8 - 6.3) and 129 staff out of 510 (25.3%, 95% CI: 21.5 - 29.1) displayed COVID-19 symptoms, including six and eight confirmed, respectively. Residents reported cough symptoms with no fever (29.3%), followed by a cough and fever (15.5%). 62.1% of symptomatic residents were 50 years or older, placing them in the group at risk for severe COVID-19 disease. Wing I had the highest attack rate (12.5%). 1,063 individuals were swabbed during the 5-day screening event, and all had negative swab results.

CONCLUSION

The findings were consistent with the hypothesis of a propagating outbreak with decreasing incidence since the peak date of onset. COVID-19 transmission within a high-risk setting was quickly contained, and an explosive outbreak was prevented through a multi-agency public health response.

摘要

目的

描述在一个有大量临床脆弱居民的大型监狱中对 COVID-19 的公共卫生应对措施。

设计

对所有居民和工作人员进行了暴发调查。一项筛查活动涉及从居民和工作人员中采集鼻和咽喉拭子样本,通过聚合酶链反应(PCR)进行检查。向工作人员分发了一份关于危险因素的电子问卷。

结果

在 1156 名居民中,有 58 名(5.0%,95%CI:3.8-6.3)出现 COVID-19 症状,包括 6 名确诊患者和 8 名疑似患者。在 510 名工作人员中,有 129 名(25.3%,95%CI:21.5-29.1)出现 COVID-19 症状,包括 8 名确诊患者和 4 名疑似患者。居民报告的症状包括无热咳嗽(29.3%),其次是咳嗽伴发热(15.5%)。62.1%有症状的居民年龄在 50 岁或以上,属于 COVID-19 重症高危人群。I 翼楼的发病率最高(12.5%)。在为期 5 天的筛查活动中,共对 1063 人进行了拭子检测,所有检测结果均为阴性。

结论

研究结果与流行爆发假设一致,即自发病高峰日以来发病率呈下降趋势。在高危环境中,COVID-19 的传播很快得到控制,多机构公共卫生应对措施防止了疫情爆发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a93/7836881/e167e806b610/gr1_lrg.jpg

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