穴位敷贴治疗功能性便秘的有效性：荟萃分析和数据挖掘的方案。
The effectiveness of acupoint herbal patching for functional constipation: Protocol for a meta-analysis and data mining.
机构信息
School of Acupuncture-Moxibustion and Tuina.
Graduate school, Changchun University of Chinese Medicine.
出版信息
Medicine (Baltimore). 2021 Jan 15;100(2):e24029. doi: 10.1097/MD.0000000000024029.
BACKGROUND
Functional constipation is a common functional problem of the digestive system that has a negative impact on physical, mental health of patients and quality of life. At present, acupoint herbal patching as an adjuvant therapy is currently undergoing clinical trials in different medical centers. However, no relevant systematic review or meta-analysis has been designed to evaluate the effects of acupoint herbal patching on functional constipation. There is also a lack of systematic evaluation and analysis of acupoints and herbs.
METHODS
We will search the following 8 databases from their inception to November 15, 2020, without language restrictions: the Cochrane Central Register of Controlled Trials, PubMed, Embase, the Web of Science, the Chinese Biomedical Literature Database, the Chinese Scientific Journal Database, the Wan-Fang Database and the China National Knowledge Infrastructure. The primary outcome measures will be clinical effective rate, functional outcomes, and quality of life. Data that meets the inclusion criteria will be extracted and analyzed using RevMan V.5.3 software. Two reviewers will evaluate the studies using the Cochrane Collaboration risk of bias tool. We will use the GRADE approach to assess the overall quality of evidence supporting the primary outcomes. We will also use Spass software (Version19.0) for complex network analysis to explore the potential core prescription of acupoint herbal patching for functional constipation.
RESULTS
This study will analyze the clinical effective rate, functional outcomes, quality of life, improvement of clinical symptoms of functional constipation, and effective prescriptions of acupoint herbal patching for patients with functional constipation.
CONCLUSION
Our findings will provide evidence for the effectiveness and potential treatment prescriptions of acupoint herbal patching for patients with functional constipation.
PROSPERO REGISTRATION NUMBER
PROSPERO CRD 42020193489.
背景
功能性便秘是一种常见的消化系统功能性问题，对患者的身心健康和生活质量有负面影响。目前，穴位敷贴作为一种辅助治疗方法正在不同的医疗中心进行临床试验。然而，目前尚未设计相关的系统评价或荟萃分析来评估穴位敷贴对功能性便秘的疗效。此外，对穴位和草药也缺乏系统的评价和分析。
方法
我们将从建库到 2020 年 11 月 15 日，在以下 8 个数据库中进行检索，不限制语言：Cochrane 对照试验中心注册库、PubMed、Embase、Web of Science、中国生物医学文献数据库、中国科学引文数据库、万方数据库和中国知网。主要结局指标为临床有效率、功能结局和生活质量。符合纳入标准的数据将使用 RevMan V.5.3 软件进行提取和分析。两位评价者将使用 Cochrane 协作风险偏倚工具评估研究。我们将使用 GRADE 方法评估支持主要结局的证据的总体质量。我们还将使用 Spass 软件（版本 19.0）进行复杂网络分析，以探讨穴位敷贴治疗功能性便秘的潜在核心处方。
结果
本研究将分析穴位敷贴治疗功能性便秘的临床有效率、功能结局、生活质量、改善临床症状以及有效处方。
结论
我们的研究结果将为穴位敷贴治疗功能性便秘的有效性和潜在治疗处方提供证据。
PROSPERO 注册号：PROSPERO CRD 42020193489。
Zotero 插件