Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine Universitas Airlangga, Airlangga University Hospital, dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.
Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Gyeonggi-do, Republic of Korea.
Medicine (Baltimore). 2021 Jan 15;100(2):e24063. doi: 10.1097/MD.0000000000024063.
This study aims to evaluate the association between target vessel size and graft patency in the right IMA-right coronary territory anastomosis.A total of 402 patients who underwent CABG between 2005 and 2016 using the right IMA Y-graft to the posterolateral branch or posterior descending artery were enrolled. Preoperative coronary angiography was utilized to measure the size of the target coronary arteries in the right territory. Follow-up angiography and computed tomography at 6 to 12 months were used to determine graft patency.Thirty patients (7.5%) were found to have occluded graft. Larger target vessel size was associated with lower risk of graft occlusion (OR: 0.18, 95% CI:0.05-0.62, P = .007). The receiver operating characteristic (ROC) curve showed that the cutoff-value of 1.93 mm was found to have the maximum sum of sensitivity and specificity for graft patency (Area under the curve (AUC): 0.65, P = .01). Excluding patients with right coronary artery total occlusion, the discriminative performance of target vessel size became more prominent (AUC: 0.76, P < .01), with same cutoff value.In the setting of bilateral IMA composite grafting, the patency of right IMA to right coronary territory was influenced by the size of the target coronary artery. The influence of target coronary artery size was prominent in non-total occlusion patients. Careful selection of a target anastomosis site is recommended.
本研究旨在评估靶血管大小与右胸廓内动脉-右冠状动脉吻合术通畅性之间的关联。共纳入 402 例 2005 年至 2016 年期间接受右胸廓内动脉 Y 型移植物至后外侧支或后降支的 CABG 患者。术前冠状动脉造影用于测量右区域靶冠状动脉的大小。术后 6-12 个月进行随访血管造影和计算机断层扫描,以确定移植物通畅性。30 例(7.5%)患者的移植物闭塞。靶血管越大,移植物闭塞的风险越低(OR:0.18,95%CI:0.05-0.62,P=0.007)。受试者工作特征(ROC)曲线显示,1.93mm 的截断值具有最大的敏感性和特异性之和,用于预测移植物通畅性(曲线下面积(AUC):0.65,P=0.01)。排除右冠状动脉完全闭塞的患者后,靶血管大小的判别性能更为显著(AUC:0.76,P<0.01),截断值相同。在双侧胸廓内动脉复合移植的情况下,右胸廓内动脉至右冠状动脉区域的通畅性受靶冠状动脉大小的影响。靶冠状动脉大小的影响在非完全闭塞患者中更为显著。建议仔细选择靶吻合部位。