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中风后失语症患者弓形束和钩束的纤维束成像改变

Tractography Alterations in the Arcuate and Uncinate Fasciculi in Post-Stroke Aphasia.

作者信息

Kierońska Sara, Świtońska Milena, Meder Grzegorz, Piotrowska Magdalena, Sokal Paweł

机构信息

Department of Neurosurgery and Neurology, Jan Biziel University Hospital No. 2, Collegium Medicum, Nicolaus Copernicus University, 85-168 Bydgoszcz, Poland.

Faculty of Health Science, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.

出版信息

Brain Sci. 2021 Jan 5;11(1):53. doi: 10.3390/brainsci11010053.

DOI:10.3390/brainsci11010053
PMID:33466403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7824889/
Abstract

Fiber tractography based on diffuse tensor imaging (DTI) can reveal three-dimensional white matter connectivity of the human brain. Tractography is a non-invasive method of visualizing cerebral white matter structures in vivo, including neural pathways surrounding the ischemic area. DTI may be useful for elucidating alterations in brain connectivity resulting from neuroplasticity after stroke. We present a case of a male patient who developed significant mixed aphasia following ischemic stroke. The patient had been treated by mechanical thrombectomy followed by an early rehabilitation, in conjunction with transcranial direct current stimulation (tDCS). DTI was used to examine the arcuate fasciculus and uncinate fasciculus upon admission and again at three months post-stroke. Results showed an improvement in the patient's symptoms of aphasia, which was associated with changes in the volume and numbers of tracts in the uncinate fasciculus and the arcuate fasciculus.

摘要

基于弥散张量成像(DTI)的纤维束成像能够揭示人类大脑的三维白质连接。纤维束成像是一种在体内可视化脑白质结构的非侵入性方法,包括缺血区域周围的神经通路。DTI可能有助于阐明中风后神经可塑性导致的脑连接改变。我们报告一例男性患者,其在缺血性中风后出现严重的混合性失语。该患者接受了机械取栓治疗,随后进行早期康复,并结合经颅直流电刺激(tDCS)。在入院时以及中风后三个月再次使用DTI检查弓形束和钩束。结果显示患者失语症状有所改善,这与钩束和弓形束的束体积和数量变化有关。

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本文引用的文献

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Tractography-Based Analysis of Morphological and Anatomical Characteristics of the Uncinate Fasciculus in Human Brains.基于纤维束成像的人脑钩束形态学和解剖学特征分析
Brain Sci. 2020 Oct 6;10(10):709. doi: 10.3390/brainsci10100709.
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Neuroimaging in Acute Stroke.急性卒中的神经影像学
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Predicting Early Post-stroke Aphasia Outcome From Initial Aphasia Severity.根据初始失语严重程度预测脑卒中后失语早期结局
皮质小脑白质完整性与脑卒中后失语症的命名结果相关。
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Tractography-guided surgery of brain tumours: what is the best method to outline the corticospinal tract?脑肿瘤追踪导向手术:勾画皮质脊髓束的最佳方法是什么?
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Neuroradiology. 2020 Apr;62(4):483-494. doi: 10.1007/s00234-019-02350-6. Epub 2019 Dec 27.
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Role of Rehabilitation in Neural Plasticity.康复在神经可塑性中的作用。
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Diffusion Tensor Imaging Biomarkers to Predict Motor Outcomes in Stroke: A Narrative Review.用于预测中风运动结局的扩散张量成像生物标志物:一项叙述性综述。
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