白种人和中国重症肌无力患者的免疫球蛋白同种异型：与日本患者的差异。
Immunoglobulin allotypes in caucasian and Chinese myasthenia gravis: differences from Japanese patients.
作者信息
Chiu H C, de Lange G G, Willcox N, Vincent A, Newsom-Davis J, Hsieh K H, Hung T P
机构信息
Department of Neurology, National Taiwan University Hospital, Taipei.
出版信息
J Neurol Neurosurg Psychiatry. 1988 Feb;51(2):214-7. doi: 10.1136/jnnp.51.2.214.
Abstract
The G2m(n) allotype was significantly increased in Chinese female and high autoantibody cases, and in caucasians with pure ocular myasthenia, or undetectable autoantibody. In contrast to the strong Glm(x) association reported in Japanese, no overall Gm haplotype, or Am or Km allotype association was found in 90 (Taiwan) Chinese and 181 caucasian myasthenia gravis patients.
摘要
G2m(n) 同种异型在中国女性和高自身抗体病例中显著增加，在患有单纯眼肌型重症肌无力或自身抗体检测不到的白种人中也显著增加。与日本报道的强烈的 Glm(x) 关联相反，在90例（台湾）中国重症肌无力患者和181例白种人重症肌无力患者中，未发现总体Gm单倍型、Am或Km同种异型的关联。
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Brain. 1980 Sep;103(3):579-601. doi: 10.1093/brain/103.3.579.
2
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Dtsch Med Wochenschr. 1983 May 6;108(18):694-700. doi: 10.1055/s-2008-1069623.
3
4
Gm allotypes in Swedish myasthenia gravis patients.瑞典重症肌无力患者的Gm同种异型
J Immunogenet. 1983 Feb;10(1):1-9. doi: 10.1111/j.1744-313x.1983.tb01010.x.
5
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J Neurol Neurosurg Psychiatry. 1984 May;47(5):555-7. doi: 10.1136/jnnp.47.5.555.
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J Immunogenet. 1984 Jun-Aug;11(3-4):173-80. doi: 10.1111/j.1744-313x.1984.tb01054.x.
7
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