School of Engineering, Information Technology and Physical Sciences, Mount Helen Campus, Federation University Australia, Ballarat, VIC 3353, Australia.
Department of Geology, University of Johannesburg, Johannesburg 2006, South Africa.
Int J Environ Res Public Health. 2021 Jan 16;18(2):740. doi: 10.3390/ijerph18020740.
The foremost mortality-causing symptom associated with COVID-19 is acute respiratory distress syndrome (ARDS). A significant correlation has been identified between the deficiency in vitamin D and the risk of developing ARDS. It has been suggested that if we can reduce or modify ARDS in COVID-19 patients, we may significantly reduce the severity of COVID-19 symptoms and associated mortality rates. The increased mortality of dark-skinned people, who have a reduced UV absorption capacity, may be consistent with diminished vitamin D status. The factors associated with COVID-19 mortality, such as old age, ethnicity, obesity, hypertension, cardiovascular diseases, and diabetes, are all found to be linked with vitamin D deficiency. Based on this review and as a precautionary measure, it is suggested that the adoption of appropriate and safe solar exposure and vitamin D enriched foods and supplements should be considered to reduce the possible severity of COVID-19 symptoms. Safe sun exposure is deemed beneficial globally, specifically in low and middle-income countries, as there is no cost involved. It is also noted that improved solar exposure and vitamin D levels can reduce the impact of other diseases as well, thus assisting in maintaining general human well-being.
与 COVID-19 相关的首要致死症状是急性呼吸窘迫综合征（ARDS）。维生素 D 缺乏与 ARDS 发病风险之间存在显著相关性。有研究表明，如果我们能够降低或改变 COVID-19 患者的 ARDS，我们可能会显著降低 COVID-19 症状的严重程度和相关死亡率。皮肤较黑的人死亡率较高，这可能与他们的紫外线吸收能力降低有关，维生素 D 状态也可能较差。与 COVID-19 死亡率相关的因素，如年龄、种族、肥胖、高血压、心血管疾病和糖尿病，都与维生素 D 缺乏有关。基于这篇综述以及作为预防措施，建议采取适当和安全的阳光暴露和富含维生素 D 的食物和补充剂，以降低 COVID-19 症状的可能严重程度。安全的阳光暴露被认为在全球范围内有益，特别是在低收入和中等收入国家，因为这不需要成本。此外，还注意到改善的阳光暴露和维生素 D 水平也可以减轻其他疾病的影响，从而有助于维持人类整体健康。
