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最佳太阳辐射暴露或补充维生素 D 摄入能否减轻 COVID-19 症状的严重程度?

Can Optimum Solar Radiation Exposure or Supplemented Vitamin D Intake Reduce the Severity of COVID-19 Symptoms?

机构信息

School of Engineering, Information Technology and Physical Sciences, Mount Helen Campus, Federation University Australia, Ballarat, VIC 3353, Australia.

Department of Geology, University of Johannesburg, Johannesburg 2006, South Africa.

出版信息

Int J Environ Res Public Health. 2021 Jan 16;18(2):740. doi: 10.3390/ijerph18020740.

Abstract

The foremost mortality-causing symptom associated with COVID-19 is acute respiratory distress syndrome (ARDS). A significant correlation has been identified between the deficiency in vitamin D and the risk of developing ARDS. It has been suggested that if we can reduce or modify ARDS in COVID-19 patients, we may significantly reduce the severity of COVID-19 symptoms and associated mortality rates. The increased mortality of dark-skinned people, who have a reduced UV absorption capacity, may be consistent with diminished vitamin D status. The factors associated with COVID-19 mortality, such as old age, ethnicity, obesity, hypertension, cardiovascular diseases, and diabetes, are all found to be linked with vitamin D deficiency. Based on this review and as a precautionary measure, it is suggested that the adoption of appropriate and safe solar exposure and vitamin D enriched foods and supplements should be considered to reduce the possible severity of COVID-19 symptoms. Safe sun exposure is deemed beneficial globally, specifically in low and middle-income countries, as there is no cost involved. It is also noted that improved solar exposure and vitamin D levels can reduce the impact of other diseases as well, thus assisting in maintaining general human well-being.

摘要

与 COVID-19 相关的首要致死症状是急性呼吸窘迫综合征(ARDS)。维生素 D 缺乏与 ARDS 发病风险之间存在显著相关性。有研究表明,如果我们能够降低或改变 COVID-19 患者的 ARDS,我们可能会显著降低 COVID-19 症状的严重程度和相关死亡率。皮肤较黑的人死亡率较高,这可能与他们的紫外线吸收能力降低有关,维生素 D 状态也可能较差。与 COVID-19 死亡率相关的因素,如年龄、种族、肥胖、高血压、心血管疾病和糖尿病,都与维生素 D 缺乏有关。基于这篇综述以及作为预防措施,建议采取适当和安全的阳光暴露和富含维生素 D 的食物和补充剂,以降低 COVID-19 症状的可能严重程度。安全的阳光暴露被认为在全球范围内有益,特别是在低收入和中等收入国家,因为这不需要成本。此外,还注意到改善的阳光暴露和维生素 D 水平也可以减轻其他疾病的影响,从而有助于维持人类整体健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb6f/7829816/65a771523610/ijerph-18-00740-g001.jpg

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