• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

体育活动对神经退行性疾病患者的有益影响。

Beneficial Effects of Physical Activity on Subjects with Neurodegenerative Disease.

作者信息

Vizzi Laura, Padua Elvira, D'Amico Agata Grazia, Tancredi Virginia, D'Arcangelo Giovanna, Cariati Ida, Scimeca Manuel, Maugeri Grazia, D'Agata Velia, Montorsi Michela

机构信息

Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy.

Department of Drug Science, University of Catania, 95125 Catania, Italy.

出版信息

J Funct Morphol Kinesiol. 2020 Dec 16;5(4):94. doi: 10.3390/jfmk5040094.

DOI:10.3390/jfmk5040094
PMID:33467309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7804865/
Abstract

Studies on the effectiveness of physical exercise to treat and/or prevent mental disorders are essential and particularly appropriate, given the rapid growth of the elderly population and the consequent increase in the prevalence of neurodegenerative diseases. The onset of neurodegenerative diseases is subtle, and progression is irreversible, as there is still no cure capable of stopping them permanently. Therefore, we should not underestimate these diseases and should immediately begin to combine the treatment with physical activity adapted to specific needs. Indeed, it is well known that physical activity has positive effects on mobility, autonomy, and functional capacity, improving not only cognitive functions, but also reducing the risk of developing dementia. Despite several studies in this field, to date there are no specific and effective protocols that promote physical exercise in people with dementia. Based on this evidence, the aim of the present work was to verify whether an adapted physical exercise regimen could promote the maintenance of psychomotor functions in elderly subjects and, therefore, delay the irreversible effects of combinations of dementia and other pathologies associated with aging. Our results clearly show that exercise is very effective in improving psychomotor functions and delaying the progress of neurodegenerative diseases in humans, since we observed that the subjects maintained their cognitive skills after 8 months of physical activity, moreover, two patients presented an amelioration. Based on the results obtained, we recommend that the motor practice, in any chosen form, be considered an integral part of prevention programs based on an active lifestyle in older people. Future studies will be necessary to establish how long lasting the benefits of a specific physical activity are and whether they are enough to delay cognitive decline.

摘要

鉴于老年人口的快速增长以及神经退行性疾病患病率的相应增加,关于体育锻炼治疗和/或预防精神障碍有效性的研究至关重要且尤为恰当。神经退行性疾病的发病较为隐匿,且进展不可逆,因为目前仍没有能够永久阻止其发展的治愈方法。因此,我们不应低估这些疾病,应立即开始将治疗与适应特定需求的体育活动相结合。事实上,众所周知,体育活动对 mobility、自主性和功能能力有积极影响,不仅能改善认知功能,还能降低患痴呆症的风险。尽管该领域已有多项研究,但迄今为止,尚无促进痴呆症患者体育锻炼的具体有效方案。基于这一证据,本研究的目的是验证一种适应性体育锻炼方案是否能促进老年受试者心理运动功能的维持,从而延缓痴呆症与其他衰老相关病症组合的不可逆影响。我们的结果清楚地表明,运动在改善人类心理运动功能和延缓神经退行性疾病进展方面非常有效,因为我们观察到,经过8个月的体育活动后,受试者保持了他们的认知技能,此外,两名患者病情有所改善。基于所获得的结果,我们建议,任何形式的运动实践都应被视为基于老年人积极生活方式的预防计划的一个组成部分。未来有必要开展研究,以确定特定体育活动的益处能持续多久,以及它们是否足以延缓认知衰退。

相似文献

1
Beneficial Effects of Physical Activity on Subjects with Neurodegenerative Disease.体育活动对神经退行性疾病患者的有益影响。
J Funct Morphol Kinesiol. 2020 Dec 16;5(4):94. doi: 10.3390/jfmk5040094.
2
Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced?丰富化对成人认知发展的影响:老年人的功能能力能否得到保持和增强?
Psychol Sci Public Interest. 2008 Oct;9(1):1-65. doi: 10.1111/j.1539-6053.2009.01034.x. Epub 2008 Oct 1.
3
4
[Recommendations for cardiovascular rehabilitation in the very elderly].[高龄老年人心血管康复的建议]
Monaldi Arch Chest Dis. 2003 Mar;60(1):25-39.
5
[Strategies to prevent age-related cognitive decline].[预防与年龄相关的认知衰退的策略]
Dtsch Med Wochenschr. 2020 Feb;145(3):146-150. doi: 10.1055/a-0955-9587. Epub 2020 Feb 4.
6
Biochemical, Biomedical and Metabolic Aspects of Imidazole-Containing Dipeptides with the Inherent Complexity to Neurodegenerative Diseases and Various States of Mental Well-Being: A Challenging Correction and Neurotherapeutic Pharmaceutical Biotechnology for Treating Cognitive Deficits, Depression and Intellectual Disabilities.含咪唑二肽的生化、生物医学及代谢方面,其与神经退行性疾病和各种精神状态的内在复杂性:用于治疗认知缺陷、抑郁症和智力障碍的具有挑战性的纠正和神经治疗药物生物技术。
Curr Pharm Biotechnol. 2014;15(8):738-78. doi: 10.2174/1389201015666140827104918.
7
[The effect of physical activity on dementia].[体育活动对痴呆症的影响]
Psychiatriki. 2019 Apr-Jun;30(2):142-155. doi: 10.22365/jpsych.2019.302.142.
8
Promoting Well-Being in Old Age: The Psychological Benefits of Two Training Programs of Adapted Physical Activity.促进老年人的幸福:两项适应性体育活动训练计划的心理益处。
Front Psychol. 2018 May 28;9:828. doi: 10.3389/fpsyg.2018.00828. eCollection 2018.
9
Comparative Cognitive Effects of Choreographed Exercise and Multimodal Physical Therapy in Older Adults with Amnestic Mild Cognitive Impairment: Randomized Clinical Trial.编舞运动与多模式物理治疗对遗忘型轻度认知障碍老年人认知影响的比较:随机临床试验。
J Alzheimers Dis. 2020;73(2):769-783. doi: 10.3233/JAD-190552.
10
Physical activity programs for persons with dementia.针对痴呆症患者的体育活动计划。
Cochrane Database Syst Rev. 2008 Jul 16(3):CD006489. doi: 10.1002/14651858.CD006489.pub2.

引用本文的文献

1
Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications.神经退行性疾病中的身体活动与神经可塑性:运动干预、认知训练及人工智能应用的综合综述
Front Neurosci. 2025 Feb 28;19:1502417. doi: 10.3389/fnins.2025.1502417. eCollection 2025.
2
The Role of Physical Activity in Adjunctive Nursing Management of Neuro-Degenerative Diseases among Older Adults: A Systematic Review of Interventional Studies.体育活动在老年人神经退行性疾病辅助护理管理中的作用:干预性研究的系统评价
Life (Basel). 2024 May 7;14(5):597. doi: 10.3390/life14050597.
3
The Interplay of Sports and Nutrition in Neurological Health and Recovery.运动与营养在神经健康和恢复中的相互作用。
J Clin Med. 2024 Apr 2;13(7):2065. doi: 10.3390/jcm13072065.
4
Effects of Different Kinds of Physical Activity on Vascular Function.不同类型体育活动对血管功能的影响。
J Clin Med. 2023 Dec 27;13(1):152. doi: 10.3390/jcm13010152.
5
Whole Body Vibration: A Valid Alternative Strategy to Exercise?全身振动:一种有效的替代性锻炼策略?
J Funct Morphol Kinesiol. 2022 Nov 3;7(4):99. doi: 10.3390/jfmk7040099.
6
The effects of active rehabilitation on symptoms associated with tau pathology: An umbrella review. Implications for chronic traumatic encephalopathy symptom management.主动康复对与 tau 病理学相关症状的影响:伞式综述。对慢性创伤性脑病症状管理的启示。
PLoS One. 2022 Jul 21;17(7):e0271213. doi: 10.1371/journal.pone.0271213. eCollection 2022.
7
Neuroprotective Effects of Physical Activity via the Adaptation of Astrocytes.运动通过星形胶质细胞适应的神经保护作用。
Cells. 2021 Jun 18;10(6):1542. doi: 10.3390/cells10061542.

本文引用的文献

1
Association of Daily Step Count and Step Intensity With Mortality Among US Adults.美国成年人的日常步数和步频与死亡率的关系。
JAMA. 2020 Mar 24;323(12):1151-1160. doi: 10.1001/jama.2020.1382.
2
Prevention of dementia in an ageing world: Evidence and biological rationale.在老龄化世界中预防痴呆症:证据和生物学原理。
Ageing Res Rev. 2020 Dec;64:101045. doi: 10.1016/j.arr.2020.101045. Epub 2020 Mar 19.
3
Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI.海马体可塑性是认知障碍患者经抗阻运动后长期认知获益的基础。
Neuroimage Clin. 2020;25:102182. doi: 10.1016/j.nicl.2020.102182. Epub 2020 Jan 14.
4
Aging, lifestyle and dementia.衰老、生活方式与痴呆。
Neurobiol Dis. 2019 Oct;130:104481. doi: 10.1016/j.nbd.2019.104481. Epub 2019 May 25.
5
Fitness, independent of physical activity is associated with cerebral blood flow in adults at risk for Alzheimer's disease.无论身体活动如何,健康与阿尔茨海默病高危成年人的大脑血流有关。
Brain Imaging Behav. 2020 Aug;14(4):1154-1163. doi: 10.1007/s11682-019-00068-w.
6
The Physical Activity Guidelines for Americans.美国人体育活动指南。
JAMA. 2018 Nov 20;320(19):2020-2028. doi: 10.1001/jama.2018.14854.
7
[Epidemiology of Alzheimer's disease and other dementias].[阿尔茨海默病及其他痴呆症的流行病学]
Rev Neurol. 2018 Jun 1;66(11):377-386.
8
[Definition and prevalence of mild cognitive impairment].[轻度认知障碍的定义与患病率]
Rev Esp Geriatr Gerontol. 2017 Jun;52 Suppl 1:3-6. doi: 10.1016/S0211-139X(18)30072-6.
9
Benefits of Exercise in the Older Population.运动对老年人群的益处。
Phys Med Rehabil Clin N Am. 2017 Nov;28(4):659-669. doi: 10.1016/j.pmr.2017.06.001.
10
[Health benefits of aerobic training programs in adults aged 70 or over: A systematic review].[70岁及以上成年人有氧训练计划的健康益处:一项系统综述]
Presse Med. 2017 Sep;46(9):794-807. doi: 10.1016/j.lpm.2017.05.028. Epub 2017 Jun 28.