7-substituted 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acids: synthesis and biological activity of a new class of quinolone antibacterials.

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作者信息

Domagala J M, Hagen S E, Heifetz C L, Hutt M P, Mich T F, Sanchez J P, Trehan A K

机构信息

Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan 48105.

出版信息

J Med Chem. 1988 Mar;31(3):503-6. doi: 10.1021/jm00398a003.

DOI:10.1021/jm00398a003

PMID:3346869

Abstract

摘要

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引用本文的文献

Fluoroquinolone antimicrobial agents.氟喹诺酮类抗菌剂。

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Structure-activity relationships of the fluoroquinolones.氟喹诺酮类药物的构效关系。

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Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems.喹诺酮类抗菌剂对真核拓扑异构酶的抑制作用及相关测试系统

Antimicrob Agents Chemother. 1990 Jan;34(1):8-12. doi: 10.1128/AAC.34.1.8.

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