Hasegawa Tsuyoshi, Sakuma Takashi, Kinoshita Haruhito, Yoshii Mami, Tamura Tatsuro, Nakamoto Kentaro, Nakagawa Yasuo, Toyokawa Takahiro, Tanaka Hiroaki, Muguruma Kazuya, Teraoka Hitoshi, Hirakawa Kosei, Ohira Masaichi
Dept. of Surgery, Baba Memorial Hospital.
Gan To Kagaku Ryoho. 2021 Jan;48(1):136-138.
Case 1: A 73-year-old man underwent total gastrectomy for residual gastric cancer, and final pathological diagnosis was pStage ⅠB. Adjuvant chemotherapy was not performed. CT findings showed multiple liver metastasis 16 months after procedure. S-1 and CDDP were administered for 28 months. Although chemotherapy regimen was changed to S-1, paclitaxel plus ramucirumab, nivolumab, irinotecan and S-1 plus oxaliplatin(SOX)after progression, he died 73 months after operation, and 57 months after recurrence. Case 2: A 72-year-old man was pointed out swelling of gastric lymph nodes in CT imaging. He was diagnosed as advanced gastric cancer with para-aortic lymph node metastasis by followed examination. S- 1 plus CDDP was administrated for 30 months. S-1 and SOX were administered after progressive findings, but he died 48 months after diagnosis. We report 2 cases of recurrent and advanced gastric cancer with long-term survival because of successful chemotherapy.
病例 1：一名 73 岁男性因残胃癌接受了全胃切除术，最终病理诊断为 p ⅠB 期。未进行辅助化疗。术后 16 个月的 CT 检查发现多处肝转移。给予 S-1 和顺铂治疗 28 个月。疾病进展后，化疗方案改为 S-1、紫杉醇联合雷莫西尤单抗、纳武单抗、伊立替康以及 S-1 联合奥沙利铂（SOX），但患者术后 73 个月、复发后 57 个月死亡。病例 2：一名 72 岁男性在 CT 影像检查中发现胃淋巴结肿大。经进一步检查，他被诊断为伴有主动脉旁淋巴结转移的进展期胃癌。给予 S-1 联合顺铂治疗 30 个月。出现病情进展后给予 S-1 和 SOX 治疗，但他在确诊后 48 个月死亡。我们报告 2 例复发性和进展期胃癌患者因化疗成功实现长期生存的病例。
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