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[通过KM-CART治疗的伴有癌性腹水且生活质量良好的乳腺癌——病例报告]

[Breast Cancer with Cancerous Ascites with Good QOL by KM-CART-A Case Report].

作者信息

Iimori Nozomi, Nishimura Shigehiko, Kushitani Yukako, Tokumoto Mao, Taenaka Naoyuki, Terashima Ken

机构信息

Dept. of Surgery, Sumitomo Hospital.

出版信息

Gan To Kagaku Ryoho. 2020 Dec;47(13):1983-1985.

PMID:33468774
Abstract

Patients with cancerous ascites often manifest with various symptoms, such as abdominal distension and poor appetite. Ascites puncture may offer temporary relief, but there is a consentration loss of important proteins, such as albumin and immunoglobulin. Cell-free and concentrated ascites reinfusion therapy(CART)is helpful to compensate for this loss of proteins. However, the volume of ascites that can be retrieved is small, and patients occasionally have high fever at the time of reinjection. CART modified by Keisuke Matsusaki(KM-CART)is an improved version of CART with respect to these points. We performed KM-CART for a woman with breast cancer with ascites arising from peritoneal dissemination, and she had a good QOL until she died. We hope that more patients will benefit from KM-CART.

摘要

癌性腹水患者常表现出各种症状,如腹胀和食欲不佳。腹水穿刺可能会提供暂时缓解,但会导致重要蛋白质如白蛋白和免疫球蛋白的浓度损失。无细胞浓缩腹水回输疗法(CART)有助于弥补这种蛋白质损失。然而,可回输的腹水量较少,且患者在回注时偶尔会出现高热。松崎启介改良的CART(KM-CART)在这些方面是CART的改进版本。我们对一名因腹膜播散导致腹水的乳腺癌女性患者进行了KM-CART治疗,她在去世前生活质量良好。我们希望更多患者能从KM-CART中受益。

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Cell-free and concentrated ascites reinfusion therapy (CART) for management of massive malignant ascites in gastric cancer patients with peritoneal metastasis treated with intravenous and intraperitoneal paclitaxel with oral S-1.采用静脉和腹腔注射紫杉醇联合口服S-1治疗的伴有腹膜转移的胃癌患者大量恶性腹水的无细胞浓缩腹水回输疗法(CART)
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