Hattori Sakurako, Wakabayashi Kazuhiko, Okazaki Sayano, Taguchi Keisuke, Minoshima Ko, Suematsu Yuki, Takahashi Miyuki, Saito Hiroyuki, Fukahori Michiko, Teranishi Nobuhisa, Ito Yutaka
Dept. of Gastroenterological Surgery, National Hospital Organization Disaster Medical Center.
Gan To Kagaku Ryoho. 2020 Dec;47(13):1994-1996.
We report a case of long-term survival in a 75-year-old male with advanced gastric cancer and Virchow's lymph node metastasis[cT3N3M1(LYM)H0P0, cStage Ⅳ]which received multidisciplinary treatment. Over 1 year and 6 months, 5 courses of S-1 plus CDDP, 14 courses of S-1 plus docetaxel, and 3 courses of S-1 plus CPT-11 were administered. Following chemotherapy, FDG-PET/CT showed FDG uptake only in the primary tumor and regional lymph nodes. Total gastrectomy and D2 dissection were performed. The pathological diagnosis was Type 5, 55×50 mm, L, Less, tub1>tub2, T3, int, INF b, ly2, v1, pPM0, pDM0, pN2(3/29), HER2(-). S-1 was used as adjuvant chemotherapy. Four years and 7 months after resection, cervical lymph node swelling was detected. The cervical lymph node was resected, followed by radiotherapy administration(56 Gy/28 Fr). No relapse occurred, and the patient has survived more than 7 years and 1 month and 8 years and 11 months after conversion surgery and diagnosis, respectively.
我们报告一例75岁晚期胃癌伴魏尔啸淋巴结转移(cT3N3M1(LYM)H0P0,c期Ⅳ)男性患者的长期生存病例,该患者接受了多学科治疗。在1年6个月的时间里,给予了5个疗程的S-1联合顺铂、14个疗程的S-1联合多西他赛以及3个疗程的S-1联合伊立替康。化疗后,FDG-PET/CT显示仅原发肿瘤和区域淋巴结有FDG摄取。进行了全胃切除术和D2淋巴结清扫术。病理诊断为5型,55×50mm,L,低分化,tub1>tub2,T3,肠型,INF b,ly2,v1,pPM0,pDM0,pN2(3/29),HER2(-)。使用S-1作为辅助化疗。切除术后4年7个月,发现颈部淋巴结肿大。切除颈部淋巴结,随后给予放射治疗(56Gy/28次分割)。未发生复发,患者分别在转化手术和诊断后存活超过7年1个月和8年11个月。