[1例胃小细胞癌术后快速复发]
[A Case of Gastric Small Cell Carcinoma with Rapid Regrowth after Surgery].
作者信息
Watanabe Megumi, Miyake Takayoshi, Mikane Yu, Syoji Ryohei, Kajiwara Yoshinori, Aoyama Katsuyuki, Nogami Tomohiro, Nishikawa Hitoshi, Shinoura Susumu, Shigemitsu Kaori, Nonaka Yasuyuki, Hayashi Dofu
机构信息
Dept. of Surgery, Tsuyama Chuo Hospital.
出版信息
Gan To Kagaku Ryoho. 2019 Jan;46(1):145-147.
The patient was a 59-year-old man with type 2 advanced gastric cancer in the antrum. Abdominal computed tomography revealed the primary tumor with regional lymph node metastasis. Distal gastrectomy and D2 lymph node dissection were performed. Histopathological findings indicated gastric small cell carcinoma. Lymph node metastasis was observed microscopically in the #6 lymph nodes. Peritoneal lavage cytology was positive. The pathologic stage of the disease was pT2(MP), med, INF b, ly2, v2, pPM0, pDM0, pN2(6/33: #5, #6), M1, P0, CY1, H0, stage Ⅳ, R1(cy+). After surgery, he received chemotherapy with capecitabine plus oxaliplatin. However, after 1 course of therapy the disease had progressed, and the patient was diagnosed with peritoneal metastasis. Chemotherapy of CDDP plus CPT-11 was initiated, and after 5 courses the patient died.
患者为一名59岁男性，患有胃窦部2期晚期胃癌。腹部计算机断层扫描显示原发性肿瘤伴有区域淋巴结转移。行远端胃切除术及D2淋巴结清扫术。组织病理学检查结果显示为胃小细胞癌。显微镜下观察到#6淋巴结有转移。腹腔灌洗细胞学检查呈阳性。疾病的病理分期为pT2(MP)，中分化，INF b，ly2，v2，pPM0，pDM0，pN2(6/33: #5, #6)，M1，P0，CY1，H0，Ⅳ期，R1(cy+)。术后，他接受了卡培他滨加奥沙利铂的化疗。然而，经过1个疗程的治疗后疾病进展，患者被诊断为腹膜转移。开始使用顺铂加伊立替康进行化疗，5个疗程后患者死亡。
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