[1例晚期胃癌伴腹膜转移经化疗（SOX方案）达到病理完全缓解]
[A Case of Advanced Gastric Cancer with Peritoneal Metastasis Achieved Pathological Complete Response by Chemotherapy(SOX Regimen)].
作者信息
Nishigaki Takahiko, Oka Yoshio, Taniguchi Hirokazu, Takahashi Kenta, Kawagishi Sachi, Yamashita Masafumi, Takeyama Hiroshi, Danno Katsuki, Toyoda Yasuhiro, Tokunaga Toshiteru, Sugimoto Keishi, Yamamoto Hitoshi, Ikeda Kimimasa
机构信息
Dept. of Surgery, Minoh City Hospital.
出版信息
Gan To Kagaku Ryoho. 2020 Dec;47(13):2281-2283.
A 68-year-old woman was presented with anorexia. Upper gastrointestinal endoscopy revealed type 4 gastric cancer at corpus of the stomach. Peritoneal metastasis was detected by staging laparoscopy. After a diagnosis of cT4aN1M1, cStage ⅣB advanced gastric cancer, we performed chemotherapy(SOX regimen; S-1 100 mg/body on day 1-14, followed by 7 days of rest, oxaliplatin 130 mg/m2 on day 1). After the 3 courses of chemotherapy, the primary tumor had been reduced. Second staging laparoscopy revealed no peritoneal metastasis. Then, we performed total gastrectomy with D2 lymph node dissection. Histopathological examination revealed no residual cancer cells, indicating a pathological complete response (Grade 3). We report a case of advanced gastric cancer with peritoneal metastasis achieved pathological complete response by chemotherapy.
一名68岁女性因厌食就诊。上消化道内镜检查显示胃体部为4型胃癌。分期腹腔镜检查发现腹膜转移。在诊断为cT4aN1M1、cStage ⅣB期进展期胃癌后，我们进行了化疗（SOX方案；S-1 100mg/体，第1 - 14天，随后休息7天，奥沙利铂130mg/m²，第1天）。3个疗程化疗后，原发肿瘤缩小。再次分期腹腔镜检查未发现腹膜转移。然后，我们进行了D2淋巴结清扫的全胃切除术。组织病理学检查显示无残留癌细胞，提示病理完全缓解（3级）。我们报告一例伴有腹膜转移的进展期胃癌通过化疗实现病理完全缓解的病例。
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