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改良版甲状腺影像报告和数据系统对高风险甲状腺结节的鉴别与管理

High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS.

作者信息

Li Menghui, Wei Lijuan, Li Fangxuan, Kan Yanyan, Liang Xiaofeng, Zhang Huan, Liu Juntian

机构信息

Cancer Prevention Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People's Republic of China.

National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, People's Republic of China.

出版信息

Cancer Manag Res. 2021 Jan 11;13:225-234. doi: 10.2147/CMAR.S284370. eCollection 2021.

Abstract

OBJECTIVE

Thyroid cancer is the most common primary malignant disorder of the thyroid. We aimed to illustrate the modified TI-RADS report system for differentiating malignant thyroid nodules from benign ones, and especially its role in the management of high risk nodules.

METHODS

In this retrospective study, 5,162 healthy individuals who underwent thyroid ultrasound according to modified TI-RADS from January 2014 to December 2014 were enrolled and followed up during the whole 5 years, and the medical data were investigated and reviewed.

RESULTS

The total detection rate of thyroid nodules was 39.40%. The total detection rate of thyroid cancer was 0.66%. Most thyroid cancers were single-shot, located at unilateral, at early clinical stages, without lymph node metastases, and with low recurrence risk. All patients had thyroid papillary carcinoma, except one thyroid medullary carcinoma. Based on modified TI-RADS classification, at the end of 5 years follow-up, more changes of thyroid nodules grade status were observed in grades 4a and above. The higher the grade status, the more malignant advances were occurred. The modified TI-RADS report system played an instructional role in adding medical treatment choice and decision for clinicians.

CONCLUSION

The modified TI-RADS report system plays an important role in thyroid benign and malignant nodule identification and management.

摘要

目的

甲状腺癌是最常见的甲状腺原发性恶性疾病。我们旨在阐述改良的甲状腺影像报告和数据系统(TI-RADS)报告系统,以区分甲状腺恶性结节和良性结节,尤其是其在高危结节管理中的作用。

方法

在这项回顾性研究中,纳入了2014年1月至2014年12月期间根据改良TI-RADS接受甲状腺超声检查的5162名健康个体,并在整个5年期间进行随访,对医疗数据进行调查和回顾。

结果

甲状腺结节的总检出率为39.40%。甲状腺癌的总检出率为0.66%。大多数甲状腺癌为单发,位于单侧,处于临床早期,无淋巴结转移,复发风险低。除1例甲状腺髓样癌外,所有患者均为甲状腺乳头状癌。基于改良TI-RADS分类,在5年随访结束时,4a级及以上甲状腺结节分级状态的变化更为明显。分级状态越高,恶性进展越明显。改良的TI-RADS报告系统在为临床医生增加治疗选择和决策方面发挥了指导作用。

结论

改良的TI-RADS报告系统在甲状腺良恶性结节的识别和管理中发挥着重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14cd/7810593/4796f91383c1/CMAR-13-225-g0001.jpg

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