Fujii M, Ishii Y, Nagao M, Wakabayashi T, Fukahori S, Goto A, Tomono T, Hagiwara K
Clinical Laboratory, Tokyo Metropolitan Cancer Detection Center.
Gan No Rinsho. 1988 Feb;34(2):174-8.
From January 1982 to March 1987, an exfoliative cytological examination of abnormal nipple discharge was carried out on 790 patients. Of 22 histologically confirmed mammary carcinomas, 7 cases (31.8%) were diagnosed as positive by conventional cytologic techniques. By using the concentration method, in which the nipple secretion was collected in a series of testings that lasted 3 to 5 days and stored in a glass tube containing a fixative, the diagnostic accuracy was seen to increase significantly and 9 out of 15 malignant cases (60.0%) were accurately diagnosed as having cancer. Moreover, all 5 cases without any palpable mass were found to be positive by the smears made by this procedure.
1982年1月至1987年3月，对790例乳头异常溢液患者进行了脱落细胞学检查。在22例经组织学确诊的乳腺癌中，7例（31.8%）经传统细胞学技术诊断为阳性。采用浓缩法，即在一系列持续3至5天的检测中收集乳头分泌物，并储存在装有固定剂的玻璃管中，诊断准确率显著提高，15例恶性病例中有9例（60.0%）被准确诊断为患有癌症。此外，通过该方法制作的涂片发现，所有5例无可触及肿块的病例均为阳性。
