Uebis R, Dörr R, Reynen K, Effert S
Abteilung Innere Medizin I der Medizinischen Fakultät der RWTH Aachen.
Klin Wochenschr. 1988;66 Suppl 12:115-8.
Following successful reperfusion of the previously occluded coronary artery in acute myocardial infarction, reocclusion remains an at least partially unsolved problem. The literature reports figures between 10 and 30%. In the present study, 130 out of 543 patients with successful thrombolysis by means of intracoronary streptokinase underwent a follow-up angiography at the 3rd day (106/130, 80%) and/or 6 months (76/130, 59%) after the acute intervention. During the observation period, neither PTCA nor bypass surgery were performed. Reocclusion could be documented in 5.5% of patients at the early stage, and in 25.0% half a year later. In more than 75% of patients, who presented with a reoccluded infarct related artery, clinical evidence of reinfarction had been recorded during the follow-up period.
在急性心肌梗死中，先前闭塞的冠状动脉成功再灌注后，再闭塞仍然是一个至少部分未解决的问题。文献报道的发生率在10%至30%之间。在本研究中，543例通过冠状动脉内链激酶成功溶栓的患者中，130例在急性干预后第3天（106/130，80%）和/或6个月（76/130，59%）接受了随访血管造影。在观察期内，未进行经皮冠状动脉腔内血管成形术（PTCA）或搭桥手术。早期有5.5%的患者记录到再闭塞，半年后为25.0%。在超过75%的梗死相关动脉再闭塞的患者中，随访期间记录到了再梗死的临床证据。
