I Department of Ophthalmology, Pomeranian Medical University, Szczecin, Poland.
Faculty of Computer Science and Information Technology, West Pomeranian University of Technology, Szczecin, Poland.
Arq Bras Oftalmol. 2021 Jan-Feb;84(1):22-30. doi: 10.5935/0004-2749.20210004.
The aim of this study was to present our own experience with the use of thermography as a complementary method for the initial diagnosis and differentiation of intraocular tumors, as well as for the evaluation of the efficacy of treatment of intraocular melanomas.
The study group comprised 37 patients with intraocular tumors, including 9 with uveal melanoma, 8 with uveal melanoma after I125 brachytherapy, 12 with a focal metastasis to the uvea, and 8 with retinal capillary hemangioblastoma. A FLIR T640 camera was used to capture images in the central point of the cornea, eye area, and orbital cavity area.
Eyes with uveal melanoma had higher temperature compared with the fellow normal eye of the patient in the range of all measured parameters in the regions of interest. In the group of patients with melanoma after unsuccessful brachytherapy, higher temperature was observed at the central point of the cornea. In patients with tumor regression, all measured parameters were lower in the affected eye. We observed lower tempe-ratures in the range of all tested parameters and areas in eyes with choroidal metastases. Eyes with diagnosed intraocular hemangioblastoma were characterized by higher parameters for the regions of interest versus eyes without this pathology.
A thermographic examination of the eye can be used as an additional first-line diagnostic tool for the differentiation of intraocular tumors. Thermography can be a helpful tool in monitoring the treatment outcome in patients with intraocular melanoma.
本研究旨在介绍我们在使用热成像作为辅助方法进行眼内肿瘤的初步诊断和鉴别诊断，以及评估眼内黑色素瘤治疗效果方面的经验。
研究组包括 37 名眼内肿瘤患者，其中 9 名患有葡萄膜黑色素瘤，8 名患有 I125 近距离放射治疗后的葡萄膜黑色素瘤，12 名患有眼内局灶转移瘤，8 名患有视网膜毛细血管瘤。使用 FLIR T640 相机在角膜中央点、眼部和眶腔区域捕获图像。
与患者对侧正常眼相比，患有葡萄膜黑色素瘤的眼在所有感兴趣区域的测量参数范围内均具有更高的温度。在近距离放射治疗失败后的黑色素瘤患者组中，角膜中央点的温度更高。在肿瘤消退的患者中，受影响眼的所有测量参数均较低。我们观察到，在所有测试参数和区域中，患有脉络膜转移瘤的眼的温度均较低。诊断为眼内毛细血管瘤的眼的感兴趣区域的参数高于没有这种病理的眼。
眼部热成像检查可作为眼内肿瘤鉴别诊断的附加一线诊断工具。热成像可以成为监测眼内黑色素瘤患者治疗效果的有用工具。
