Lomi Neiwete, Das Deepsekhar, Chawla Bhavna, Niranjana J, Rajasekaran Dhanabalan, Tandon Radhika
Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian J Ophthalmol. 2025 Aug 1;73(8):1239-1240. doi: 10.4103/IJO.IJO_24_25. Epub 2025 Jul 28.
Anterior segment tumors are rare tumors with limited management options. In small-sized lesions, plaque brachytherapy is advisable. The placement techniques of plaques for anterior segment tumors are completely different from the techniques for posterior segment tumors.[1-4] In cases where the lesion is located in the medial, lateral, or inferior iris, the possibility of tilt or displacement of the plaque is higher. The gravitational pull, coupled with ocular movements, squeezes the plaque against the ocular surface and the eyelid. This leads to displacement of the plaque along with damage to the corneal epithelium. Although certain novel plaque designs have been described in the literature to prevent such complications.[5] Their regular availability in all brachytherapy units is limited.
The authors here demonstrate a novel technique of "Triple support pocket" in a case of inferior irido-ciliary melanoma.
The video demonstrates the steps of the "triple support pocket" orientation of brachytherapy plaque placement, along with a surgical demonstration in a case of inferior irido-ciliary melanoma. The steps include first sectoral peritomy with conjunctival dissection and flap creation, followed by step 2, which involves placement of a figure of 8 pattern 5-0 ethibond suture. The points of suture entry and exit are determined by the size of the plaque. The entries and exits are 0.5-1 mm away from the plaque edge. The third step involves moving the conjunctival flap over the brachytherapy plaque. The fourth step is where a tarsorrhaphy is performed. A 42-year-old female patient presented with an inferior iris lesion, which was diagnosed as an irido-ciliary melanoma using the popular "ABCDEF" rule designed by Shield et al.[6] The tumor had a largest basal diameter of 7.32 mm and an apical thickness of 3.87 mm extending inferiorly from 6'o clock to 7'o clock. A radio-active Ruthenium 106 plaque of size 12 mm was used in the management. Centration was achieved by using ultrasound on the table. Care was taken to ensure that all the edges of the tumor is covered, and the center of the plaque corresponds to the maximum apical thickness. The authors have performed this procedure twice, and there has been no incidence of tilt of plaque or displacement. The mean duration of the two cases was 119.5 hours. Mean dose at the sclera and apex is 313 Gy and 80 Gy, respectively. At 3 months follow-up, there were no cornea-related side effects or glaucoma.
Triple support pocket orientation of plaque brachytherapy helps in the prevention of displacement or tilt of the brachytherapy plaque.
眼前节肿瘤是罕见肿瘤,治疗选择有限。对于小尺寸病变,敷贴近距离放疗是可取的。眼前节肿瘤敷贴的放置技术与眼后节肿瘤的技术完全不同。[1-4] 在病变位于虹膜内侧、外侧或下方的情况下,敷贴倾斜或移位的可能性更高。重力作用加上眼球运动,会将敷贴挤压在眼表面和眼睑上。这会导致敷贴移位以及角膜上皮受损。尽管文献中描述了某些新型敷贴设计以预防此类并发症。[5] 但它们在所有近距离放疗单位的常规可用性有限。
本文作者展示了一例下虹膜睫状体黑色素瘤的“三联支撑袋”新技术。
该视频展示了近距离放疗敷贴放置的“三联支撑袋”定位步骤,以及一例下虹膜睫状体黑色素瘤的手术演示。步骤包括首先进行扇形睑球分离术,切开结膜并制作皮瓣,接着是第二步,即放置8字形5-0聚酯缝线。缝线的进出点由敷贴大小决定。进出点距敷贴边缘0.5 - 1毫米。第三步是将结膜皮瓣移至近距离放疗敷贴上。第四步是进行睑裂缝合术。一名42岁女性患者出现下虹膜病变,使用Shield等人设计的流行的“ABCDEF”规则诊断为虹膜睫状体黑色素瘤。[6] 肿瘤最大基底直径为7.32毫米,顶端厚度为3.87毫米,从6点向下延伸至7点。治疗中使用了一块12毫米的放射性钌106敷贴。在手术台上通过超声实现中心定位。注意确保肿瘤的所有边缘都被覆盖,且敷贴中心对应最大顶端厚度。作者已进行此手术两次,未发生敷贴倾斜或移位情况。两例手术的平均时长为119.5小时。巩膜和顶端的平均剂量分别为313 Gy和80 Gy。在3个月随访时,未出现与角膜相关的副作用或青光眼。
敷贴近距离放疗的三联支撑袋定位有助于预防近距离放疗敷贴的移位或倾斜。