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SARS-CoV-2 感染活动期合并淀粉样血管病患者发生脑出血：病例报告。

Cerebral hemorrhage during the active phase of SARS-CoV-2 infection in a patient with amyloid angiopathy: case report.

机构信息

BP - A Beneficência Portuguesa de São Paulo - São Paulo (SP), Brasil.

Brazilian Research in Intensive Care Network (BRICnet) - São Paulo (SP), Brasil.

出版信息

Rev Bras Ter Intensiva. 2020 Oct-Dec;32(4):603-605. doi: 10.5935/0103-507X.20200098.

DOI:10.5935/0103-507X.20200098
PMID:33470362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7853683/
Abstract

The neurological changes associated with COVID-19 have been frequently described, especially in cases of greater severity, and are related to multifactorial causes, such as endothelial dysfunction, inflammatory mediator release (cytokine storm), endothelial dysfunction and hypoxemia. We report the case of a female patient, 88 years old, with cerebral hemorrhage associated with amyloid angiopathy in the context of SARS-CoV-2 infection.

摘要

与 COVID-19 相关的神经学改变已被频繁描述，尤其是在更严重的情况下，这些改变与多因素病因相关，如血管内皮功能障碍、炎症介质释放（细胞因子风暴）、血管内皮功能障碍和低氧血症。我们报告了一例女性患者，88 岁，在 SARS-CoV-2 感染的情况下并发与淀粉样血管病相关的脑出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf68/7853683/86601832b682/rbti-32-04-0603-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf68/7853683/86601832b682/rbti-32-04-0603-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf68/7853683/86601832b682/rbti-32-04-0603-g01.jpg

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Stroke Vasc Neurol. 2020 Sep;5(3):279-284. doi: 10.1136/svn-2020-000431. Epub 2020 Jul 2.
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Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.
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Lancet Psychiatry. 2020 Oct;7(10):875-882. doi: 10.1016/S2215-0366(20)30287-X. Epub 2020 Jun 25.
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Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review.新型冠状病毒病 2019 时代冠状病毒的神经发病机制和神经表现：综述。
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