Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Azienda Unità Sanitaria Locale (AUSL) Imola, Imola, Italy.
Cytopathology. 2021 Jul;32(4):519-522. doi: 10.1111/cyt.12954. Epub 2021 Jan 20.
Angiosarcoma of the thyroid is a rare and aggressive primary malignant tumour of the thyroid. We report the case of a 69-year-old woman who presented with a red and sore skin area at the right-anterior region of the neck. Ultrasound examination and computed tomography scan showed a non-homogeneous mass in the right thyroid lobe. Fine needle aspiration cytology was suggestive of atypical vascular proliferation and so the patient underwent right thyroid lobectomy. The specimen measured 6 × 5 × 2.5 cm, and a reddish nodule was found, including a whitish central area of maximum 4 cm in diameter. Immunohistochemistry showed CD31 and ERG positivity, while thyroglobulin, calcitonin and TTF-1 expression were negative, indicating a diagnosis of angiosarcoma.
甲状腺血管肉瘤是一种罕见且侵袭性的甲状腺原发性恶性肿瘤。我们报告了一例 69 岁女性病例，其右侧颈部前区出现红肿疼痛的皮肤区域。超声检查和计算机断层扫描显示右甲状腺叶内存在非均质肿块。细针穿刺细胞学检查提示为非典型血管增生，因此患者接受了右甲状腺叶切除术。标本大小为 6×5×2.5cm，可见一个红色小结节，其中央有一个最大直径为 4cm 的白色区域。免疫组织化学显示 CD31 和 ERG 阳性，而甲状腺球蛋白、降钙素和 TTF-1 表达为阴性，提示诊断为血管肉瘤。
