Goumas P, Trouboukis D, Toska N, Sissis T, Deftos C
Hals-Nasen-Ohren-Klinik der Universität Patras, Griechenland.
Laryngol Rhinol Otol (Stuttg). 1988 Jan;67(1):34-7.
This study reports on an immunohistochemical examination of the tonsils. For this purpose 10 clinically healthy tonsils, 15 with acute tonsillitis, 40 with chronic cryptic tonsillitis and 16 hyperplastic tonsils were studied by means of the direct immunofluorescent technique. With regard to the clinically healthy tonsils: the number, the size of the germinal centres and the density of the immunocytes in them were very large in the hyperplastic tonsils, large in chronic cryptic tonsillitis, but remarkably decreased in acute tonsillitis. The disseminated immunoglobulin of the centres also presented a significant increase in all of them. In the extrafollicular area the fluorescent immunocytes were significantly increased. Although we did not notice differences in the density of IgA and IgM immunocytes between chronic cryptic tonsillitis and hyperplastic tonsils in the acute tonsillitis IgA immunocytes were found to be increased.
本研究报告了扁桃体的免疫组织化学检查。为此，采用直接免疫荧光技术对10个临床健康扁桃体、15个急性扁桃体炎扁桃体、40个慢性隐窝性扁桃体炎扁桃体和16个增生性扁桃体进行了研究。关于临床健康扁桃体：生发中心的数量、大小及其内免疫细胞的密度在增生性扁桃体中非常大，在慢性隐窝性扁桃体炎中较大，但在急性扁桃体炎中显著降低。生发中心的弥散免疫球蛋白在所有这些扁桃体中也显著增加。在滤泡外区域，荧光免疫细胞显著增加。虽然我们未注意到慢性隐窝性扁桃体炎和增生性扁桃体之间IgA和IgM免疫细胞密度的差异，但在急性扁桃体炎中发现IgA免疫细胞增加。
