超声引导经阴道射频消融联合左炔诺孕酮宫内缓释系统治疗症状性子宫腺肌病。
Ultrasound-guided transvaginal radiofrequency ablation combined with levonorgestrel-releasing intrauterine system for symptomatic uterine adenomyosis treatment.
机构信息
Department of Ultrasound, Beijing Chaoyang Hospital Capital Medical University, Beijing, China.
Department of Gynecology, The PLA Rocket Force General Hospital, Beijing, China.
出版信息
Int J Hyperthermia. 2021;38(1):65-69. doi: 10.1080/02656736.2021.1874063.
OBJECTIVE
To evaluate the clinical outcomes of transvaginal ultrasound-guided radiofrequency ablation (RFA) combined with a levonorgestrel-releasing intrauterine system (LNG-IUS) for the treatment of symptomatic uterine adenomyosis.
METHODS
Patients with symptomatic uterine adenomyosis treated with ultrasound-guided RFA in combined with an LNG-IUS from January 2013 to January 2016 and followed up for 3 years after treatment were selected. Assessment endpoints included the uterine volume reduction rate, dysmenorrheal score, symptom severity score and adverse events.
RESULTS
Among the 72 patients, 64 completed the 3-year follow-up evaluations after treatment. No LNG-IUS expulsion was reported. Dysmenorrhea and symptom severity scores statistically significantly declined after the combined treatment of RFA and LNG-IUS was administered. The uterine volume significantly decreased, and the average reduction rate was 55%.
CONCLUSION
Ultrasound-guided RFA combined with an LNG-IUS might be a simple, safe and effective alternative for the treatment of symptomatic adenomyosis.
目的
评估经阴道超声引导下射频消融（RFA）联合左炔诺孕酮宫内缓释系统（LNG-IUS）治疗症状性子宫腺肌病的临床疗效。
方法
选取 2013 年 1 月至 2016 年 1 月期间采用超声引导下 RFA 联合 LNG-IUS 治疗的症状性子宫腺肌病患者，对患者进行 3 年的随访。评估终点包括子宫体积缩小率、痛经评分、症状严重程度评分和不良反应。
结果
72 例患者中，64 例完成了治疗后 3 年的随访评估。未发生 LNG-IUS 脱落。RFA 联合 LNG-IUS 治疗后痛经和症状严重程度评分均显著下降。子宫体积明显缩小，平均缩小率为 55%。
结论
经阴道超声引导下 RFA 联合 LNG-IUS 可能是治疗症状性腺肌病的一种简单、安全、有效的方法。
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