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单孔腹腔镜下子宫腺肌瘤切除术与子宫底切除术的手术效果比较:来自单一中心的经验

Comparison of Surgical Outcomes Between Single-Site Laparoscopic Adenomyomectomy and Fundusectomy: Experience from a Single Center.

作者信息

Jeong Jae Hyeok, Kim Yoo Ri, Kim Bo Ram, Lee Ji Won, Oh Seung Yeon, Yun Jeong Hye, Han Myoung Seok, Song Yong Jung, Kim Ki Hyung

机构信息

Department of Obstetrics and Gynecology, Yeonje Ilsin Hospital, Busan 04991, Republic of Korea.

Department of Obstetrics and Gynecology, School of Medicine, Pusan National University, Busan 46241, Republic of Korea.

出版信息

J Clin Med. 2025 Jun 7;14(12):4044. doi: 10.3390/jcm14124044.

DOI:10.3390/jcm14124044
PMID:40565790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12194309/
Abstract

: This study aimed to introduce clinical experience using a new surgical technique, single-port access laparoscopic fundusectomy, a more efficient uterus-sparing surgical method for adenomyosis in patients with no plans for pregnancy. : We performed single-port access laparoscopic myomectomy in 141 patients and single-port access laparoscopic fundusectomy in 124 patients and compared the surgical outcomes. : Significant differences in surgical outcomes were observed between the two operating methods. Operative time was 158.19 min (±42.93) in the fundusectomy group and 179.11 min (±56.95) in the adenomyomectomy group ( = 0.001). Estimated blood loss was 175.04 mL (±142.76) in the fundusectomy group and 347.97 mL (±409.78) in the adenomyomectomy group ( = 0.000). The fundusectomy group showed smaller uterus size and volume, and lower postoperative CA125 levels than the adenomyomectomy group for 24 months ( = 0.000). : This study suggests that single-port access laparoscopic fundusectomy is more effective in terms of operative time, estimated blood loss, and postoperative CA125 decrease than single-port access laparoscopic adenomyomectomy.

摘要

本研究旨在介绍一种新的手术技术——单孔腹腔镜子宫底切除术的临床经验,这是一种对无妊娠计划的子宫腺肌病患者更有效的保留子宫的手术方法。我们对141例患者进行了单孔腹腔镜子宫肌瘤切除术,对124例患者进行了单孔腹腔镜子宫底切除术,并比较了手术结果。两种手术方法的手术结果存在显著差异。子宫底切除术组的手术时间为158.19分钟(±42.93),子宫腺肌瘤切除术组为179.11分钟(±56.95)(P = 0.001)。子宫底切除术组的估计失血量为175.04毫升(±142.76),子宫腺肌瘤切除术组为347.97毫升(±409.78)(P = 0.000)。在24个月内,子宫底切除术组的子宫大小和体积较小,术后CA125水平低于子宫腺肌瘤切除术组(P = 0.000)。本研究表明,单孔腹腔镜子宫底切除术在手术时间、估计失血量和术后CA125降低方面比单孔腹腔镜子宫腺肌瘤切除术更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/d76a8a953485/jcm-14-04044-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/b0d70c6246bd/jcm-14-04044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/dd427fa9e7a1/jcm-14-04044-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/24f1f6208bd7/jcm-14-04044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/7bf99ded9df7/jcm-14-04044-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/d76a8a953485/jcm-14-04044-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/b0d70c6246bd/jcm-14-04044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/dd427fa9e7a1/jcm-14-04044-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/24f1f6208bd7/jcm-14-04044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/7bf99ded9df7/jcm-14-04044-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d7f/12194309/d76a8a953485/jcm-14-04044-g005.jpg

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本文引用的文献

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Conservative surgical treatment for adenomyosis: New options for looking beyond uterus removal.保守手术治疗子宫腺肌病:超越子宫切除的新选择。
Best Pract Res Clin Obstet Gynaecol. 2024 Jul;95:102507. doi: 10.1016/j.bpobgyn.2024.102507. Epub 2024 May 31.
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Correlation analysis of hysterectomy and ovarian preservation with depression.子宫切除术与卵巢保留与抑郁的相关性分析。
Sci Rep. 2023 Jun 16;13(1):9744. doi: 10.1038/s41598-023-36838-2.
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Pregnancy Outcomes after Uterus-sparing Operative Treatment for Adenomyosis: A Systematic Review and Meta-analysis.
子宫腺肌病保留子宫手术治疗后的妊娠结局:系统评价和荟萃分析。
J Minim Invasive Gynecol. 2023 Jul;30(7):543-554. doi: 10.1016/j.jmig.2023.03.015. Epub 2023 Mar 25.
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Risk of Recurrence and Reintervention After Uterine-Sparing Interventions for Symptomatic Adenomyosis: A Systematic Review and Meta-Analysis.子宫腺肌病症状性保宫干预后复发和再干预的风险:系统评价和荟萃分析。
Obstet Gynecol. 2023 Apr 1;141(4):711-723. doi: 10.1097/AOG.0000000000005080. Epub 2023 Mar 9.
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Adenomyomectomy: A complicated surgery.
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A systematic review of outcome reporting and outcome measures in studies investigating uterine-sparing treatment for adenomyosis.一项关于子宫腺肌病保留子宫治疗研究中结局报告和结局指标的系统评价。
Hum Reprod Open. 2021 Aug 7;2021(3):hoab030. doi: 10.1093/hropen/hoab030. eCollection 2021.
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Laparoscopically assisted Adenomyomectomy Using the Double/Multiple-Flap Method with Temporary Occlusion of the Bilateral Uterine Artery and Utero-Ovarian Vessels in Comparison with the Double/Multiple-Flap Only Method.腹腔镜辅助腺肌病切除术:采用双侧子宫动脉和子宫卵巢血管临时阻断的双瓣/多瓣法与单纯双瓣/多瓣法的比较
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High-intensity focused ultrasound in the management of adenomyosis: long-term results from a single center.高强度聚焦超声在子宫腺肌病治疗中的应用:单中心长期结果。
Int J Hyperthermia. 2021;38(1):241-247. doi: 10.1080/02656736.2021.1886347.
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