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超声测量仰卧位下右股总静脉横径预测剖宫产术中脊麻后低血压。

The transverse diameter of right common femoral vein by ultrasound in the supine position for predicting post-spinal hypotension during cesarean delivery.

机构信息

Department of B ultrasound, the International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.

出版信息

BMC Anesthesiol. 2021 Jan 20;21(1):22. doi: 10.1186/s12871-021-01242-8.

Abstract

BACKGROUND

Post-spinal anesthesia hypotension during cesarean delivery is caused by decreased systemic vascular resistance due to the blockage of the autonomic nerves, which is further worsened by inferior vena cava (IVC) compression by the gravid uterus. This study aimed to assess whether peak velocity and diameter of the IVC below the xiphoid or right common femoral vein (RCFV) in the inguinal region, as measured on ultrasound, could reflect the degree of IVC compression and further identify parturients at risk of post-spinal hypotension.

METHODS

Fifty-six parturients who underwent elective cesarean section with spinal anesthesia were included in this study; peak velocities and anteroposterior diameters of the IVC and peak velocities and transverse diameters of the RCFV were measured using ultrasound before anesthesia. The primary outcome was the ultrasound measurements of IVC and RCFV acquired before spinal anesthesia and their association with post-spinal hypotension. Hypotension was defined as a drop in systolic arterial pressure by > 20% from the baseline. Multinomial logistic regression analysis was used to identify the association between the measurements of IVC, RCFV, and post-spinal hypotension during cesarean delivery. Receiver operating characteristic curves were used to test the abilities of the identified parameters to predict post-spinal hypotension; the areas under the curve and optimum cut-off values for the predictive parameters were calculated.

RESULTS

A longer transverse diameter of the RCFV was associated with the occurrence of post-spinal hypotension (odds ratio = 2.022, 95% confidence interval [CI] 1.261-3.243). The area under the receiver operating characteristics curve for the prediction of post-spinal hypotension was 0.759 (95% CI 0.628-0.890, P = 0.001). A transverse diameter of > 12.2 mm of the RCFV could predict post-spinal hypotension during cesarean delivery.

CONCLUSIONS

A longer transverse diameter of RCFV was associated with hypotension and could predict parturients at a major risk of hypotension before anesthesia.

TRIAL REGISTRATION

This study was registered at http://www.chictr.org.cn on 16, May, 2018. No. ChiCTR1800016163 .

摘要

背景

剖宫产术中脊麻后低血压是由于自主神经阻滞导致全身血管阻力下降引起的,而妊娠子宫对下腔静脉(IVC)的压迫进一步加重了这种情况。本研究旨在评估超声测量剑突下或右股总静脉(RCFV)下方 IVC 的峰值速度和直径是否能反映 IVC 受压程度,并进一步识别有脊麻后低血压风险的产妇。

方法

本研究纳入 56 例行择期剖宫产术的产妇,在麻醉前使用超声测量 IVC 和 RCFV 的峰值速度和前后直径,以及 RCFV 的峰值速度和横径。主要结局是脊麻前超声测量 IVC 和 RCFV,并与脊麻后低血压相关。低血压定义为收缩压从基线下降>20%。采用多项逻辑回归分析确定 IVC、RCFV 测量值与剖宫产脊麻后低血压的关系。采用受试者工作特征曲线(ROC 曲线)检验确定的参数预测脊麻后低血压的能力;计算曲线下面积(AUC)和预测参数的最佳截断值。

结果

RCFV 的横径较长与脊麻后低血压的发生相关(比值比=2.022,95%置信区间[CI] 1.261-3.243)。预测脊麻后低血压的 ROC 曲线下面积为 0.759(95%CI 0.628-0.890,P=0.001)。RCFV 的横径>12.2mm 可预测剖宫产脊麻后低血压。

结论

RCFV 的横径较长与低血压相关,并可在麻醉前预测低血压风险较大的产妇。

试验注册

本研究于 2018 年 5 月 16 日在 http://www.chictr.org.cn 注册,注册号为 ChiCTR1800016163。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d99f/7816508/9c7bfed4fe0c/12871_2021_1242_Fig1_HTML.jpg

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