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化疗与姑息性低分割放疗对猫鼻淋巴瘤的疗效

Efficacy of chemotherapy and palliative hypofractionated radiotherapy for cats with nasal lymphoma.

作者信息

Nakazawa Maho, Tomiyasu Hirotaka, Suzuki Kanako, Asada Hajime, Fujiwara-Igarashi Aki, Goto-Koshino Yuko, Ohmi Aki, Ohno Koichi, Fujita Michio, Tsujimoto Hajime

机构信息

Department of Veterinary Clinical Pathobiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.

Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.

出版信息

J Vet Med Sci. 2021 Apr 3;83(3):456-460. doi: 10.1292/jvms.20-0464. Epub 2021 Jan 20.

Abstract

Nasal lymphoma (NL) is the most common nasal tumor in cats, and radiotherapy, chemotherapy, or a combination of these treatments have been described as the treatment for this disease. However, the previous studies included various machines and protocols of radiotherapy. Therefore, we aimed to retrospectively compare the prognosis among cases treated with palliative hypofractionated radiotherapy, chemotherapy, and a combination of them with united machine and protocol of radiotherapy. When compared overall survival and progression free survival, there was no significant difference among these three groups. The data of this study suggested that similar efficacy could be achieved by palliative hypofractionated radiotherapy, chemotherapy, or a combination of them.

摘要

鼻淋巴瘤(NL)是猫最常见的鼻腔肿瘤,放疗、化疗或这些治疗方法的联合应用已被描述为该病的治疗方式。然而,先前的研究包括各种放疗设备和方案。因此,我们旨在回顾性比较接受姑息性低分割放疗、化疗以及两者联合治疗(采用统一的放疗设备和方案)的病例的预后。比较总生存期和无进展生存期时,这三组之间没有显著差异。本研究数据表明,姑息性低分割放疗、化疗或两者联合应用可取得相似的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/538c/8025413/6d9769875b9e/jvms-83-456-g001.jpg

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