Sato Hirofumi, Fujino Yasuhito, Chino Junko, Takahashi Masashi, Fukushima Kenjiro, Goto-Koshino Yuko, Uchida Kazuyuki, Ohno Koichi, Tsujimoto Hajime
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
J Vet Med Sci. 2014 Jun;76(6):807-11. doi: 10.1292/jvms.13-0260. Epub 2014 Feb 10.
The present study was carried out to analyze the prognosis of 163 cats with lymphoma classified anatomically and cytomorphologically. Anatomically, alimentary lymphoma was the most common form and showed significantly shorter survival than mediastinal and nasal lymphomas in cats. Cytomorphologically, there was no predominant subtype in feline lymphomas. Immunoblastic type (18%), centroblastic type (16%), globule leukocyte type (15%), lymphocytic type (12%), lymphoblastic type (12%), pleomorphic medium and large cell type (10%) and anaplastic large cell type (7%) were relatively common subtypes. Most of the cats with globule leukocyte lymphoma had the alimentary form. Comparing median survival time among classifications, cats with globule leukocyte lymphoma showed significantly shorter survival than those with high-grade and other low-grade lymphomas. Furthermore, cats with high-grade lymphomas showed significantly shorter survival than cats with other low-grade lymphomas. The present study indicated the clinical significance of anatomical and cytomorphological evaluation in feline lymphomas.
本研究旨在分析163只经解剖学和细胞形态学分类的猫淋巴瘤的预后情况。从解剖学角度来看，消化道淋巴瘤是最常见的形式，且猫的消化道淋巴瘤的生存期明显短于纵隔和鼻腔淋巴瘤。从细胞形态学角度来看，猫淋巴瘤中没有占主导地位的亚型。免疫母细胞型（18%）、中心母细胞型（16%）、球样白细胞型（15%）、淋巴细胞型（12%）、淋巴母细胞型（12%）、多形性中大型细胞型（10%）和间变性大细胞型（7%）是相对常见的亚型。大多数球样白细胞淋巴瘤的猫为消化道形式。比较不同分类之间的中位生存时间，球样白细胞淋巴瘤的猫的生存期明显短于高级别和其他低级别淋巴瘤的猫。此外，高级别淋巴瘤的猫的生存期明显短于其他低级别淋巴瘤的猫。本研究表明了解剖学和细胞形态学评估在猫淋巴瘤中的临床意义。
