relA基因对生长中的大肠杆菌中氨基酸生物合成酶去阻遏的影响取决于所去阻遏的途径。
Effect of the relA gene on derepression of amino acid biosynthetic enzymes in growing Escherichia coli depends on the pathway being derepressed.
作者信息
Furano A V, Wittel F P
出版信息
J Bacteriol. 1977 Oct;132(1):352-5. doi: 10.1128/jb.132.1.352-355.1977.
Abstract
Derepression of an enzyme in the arginine biosynthetic pathway, but not of an enzyme in the tryptophan biosynthetic pathway, is inhibited during the stringent response produced by a partial deprivation of valyl transfer ribonucleic acid in a rel+ strain. In contrast, derepression of the tryptophan biosynthetic enzyme, but not of the arginine biosynthetic enzyme, was inhibited during the relaxed response produced in an isogenic relA strain by the partial deprivation of valyl transfer ribonucleic acid.
摘要
在rel⁺菌株中，由于缬氨酰转移核糖核酸部分缺乏所产生的严紧反应期间，精氨酸生物合成途径中的一种酶的去阻遏受到抑制，但色氨酸生物合成途径中的酶的去阻遏未受抑制。相反，在同基因relA菌株中，由于缬氨酰转移核糖核酸部分缺乏所产生的松弛反应期间，色氨酸生物合成酶的去阻遏受到抑制，但精氨酸生物合成酶的去阻遏未受抑制。
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