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大鼠正中隆起的一些血管被血管活性肠肽/组氨酸异亮氨酸肽(VIP/PHI)免疫反应性神经的密集丛所包围。

Some blood vessels in the rat median eminence are surrounded by a dense plexus of vasoactive intestinal polypeptide/peptide histidine isoleucine (VIP/PHI) immunoreactive nerves.

作者信息

Ceccatelli S, Tsuruo Y, Hökfelt T, Fahrenkrug J, Döhler K D

机构信息

Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Neurosci Lett. 1988 Jan 11;84(1):29-34. doi: 10.1016/0304-3940(88)90332-1.

Abstract

Using immunohistochemistry at the light and electron microscopic level some blood vessels along the median eminence were shown to be surrounded by dense networks of vasoactive intestinal polypeptide/peptide histidine isoleucine (VIP/PHI)-positive fibers. VIP and PHI released from these fibers may contribute to the elevated levels of these two peptides measured in portal blood as compared to peripheral blood by radioimmunoassay. VIP and PHI may also be important in the control of blood flow through the median eminence.

摘要

利用光镜和电镜水平的免疫组织化学方法显示,沿着正中隆起的一些血管被血管活性肠肽/组异肽(VIP/PHI)阳性纤维的致密网络所包围。与外周血相比,通过放射免疫测定法测得的门静脉血中这两种肽水平升高,可能是由这些纤维释放的VIP和PHI所致。VIP和PHI在控制通过正中隆起的血流方面可能也很重要。

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