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史蒂文斯-约翰逊综合征的外阴阴道后遗症及其处理

Vulvovaginal sequelae of Stevens-Johnson syndrome and their management.

作者信息

Wilson E E, Malinak L R

机构信息

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

出版信息

Obstet Gynecol. 1988 Mar;71(3 Pt 2):478-80.

PMID:3347438
Abstract

We describe a woman with Stevens-Johnson syndrome, a life-threatening form of erythema multiforme characterized by bullae formation, extensive mucosal damage, and systemic toxicity, and known to be triggered by various drugs, infections, ingestants, or contactants. Serious complications have been reported in most body systems, including cases of permanent damage to the urogenital tract. Three methods of surgical treatment for severe vaginal complications, depending on the degree of vaginal mucosal damage, are described, including the successful treatment of our patient, who had vaginal adenosis, endometriosis, and severe stenosis from this disease. Methods of therapy are presented for possible prevention of severe vaginal sequelae from Stevens-Johnson syndrome.

摘要

我们描述了一位患有史蒂文斯-约翰逊综合征的女性,这是一种危及生命的多形红斑,其特征为水疱形成、广泛的黏膜损伤和全身毒性,已知可由多种药物、感染、摄入物或接触物引发。大多数身体系统都报告过严重并发症,包括泌尿生殖道永久性损伤的病例。本文描述了三种针对严重阴道并发症的手术治疗方法,具体取决于阴道黏膜损伤程度,其中包括对我们这位患有阴道腺病、子宫内膜异位症以及由此疾病导致的严重狭窄的患者的成功治疗。文中还介绍了可能预防史蒂文斯-约翰逊综合征所致严重阴道后遗症的治疗方法。

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