Rozner Lihi, Peles Einat
Department of Psychiatry, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Dr. Miriam and Sheldon G. Adelson Clinic for Drug Abuse Treatment and Research, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Harefuah. 2021 Jan;160(1):19-23.
Opioids play a key role in managing acute and chronic pain, but at the same time, opioid abuse is a socio-economic and health problem that has been expanding over the past three decades, causing a high rate of morbidity and mortality. Methadone maintenance therapy is the most effective treatment choice (combined with psychosocial therapy) for opioid addiction. However, only a small proportion of people with opioid addiction turn to this treatment. In addition, patients applying for methadone maintenance treatment do so with great delay, after 10 and even 20 years of addiction. A possible explanation for this phenomenon discussed in the medical literature is stigma and misinformation about methadone maintenance therapy in patients with substance use disorder, society, family of patients, and healthcare professionals.
阿片类药物在急性和慢性疼痛管理中发挥着关键作用,但与此同时,阿片类药物滥用是一个社会经济和健康问题,在过去三十年中一直在扩大,导致高发病率和死亡率。美沙酮维持治疗是治疗阿片类药物成瘾最有效的选择(结合心理社会治疗)。然而,只有一小部分阿片类药物成瘾者会寻求这种治疗。此外,申请美沙酮维持治疗的患者延迟时间很长,在成瘾10年甚至20年后才这样做。医学文献中讨论的这种现象的一个可能解释是,物质使用障碍患者、社会、患者家属和医疗保健专业人员对美沙酮维持治疗存在污名化和错误信息。